Paper Information

Journal:   IRANIAN JOURNAL OF PUBLIC HEALTH   AUGUST 2014 , Volume 43 , Number SUPPLEMENT 2; Page(s) 38 To 38.
 
Paper: 

EVALUATION OF ANTIBACTERIAL EFFECT OF ECHIUM AMOENUM FISCH. ET MEY.ON MULTIDRUG RESISTANCE ACINETOBACTER BAUMANNII ISOLATES FROM CLINICAL SAMPLES OF BURN WOUNDS

 
 
Author(s):  SABOUR MANDANA*, HAKEMI VALA MOJDEH, OSTAD ASADOLLAH MALAYERI HELIA
 
* PHARMACEUTICAL SCIENCES BRANCH, ISLAMIC AZAD UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Background: Borage (Echium amoenum Fisch. et Mey), is a wild member of Boraginaceae. This plant grows in different countries and also northern mountains of Iran. This medicinal plant has largely been used by Iranian folk as a mood enhancer, an anxiolytic, an inflammatory, laxative, emollients and also for treatment of infectious diseases. In this study the methanolic extract of dried flowers of Echium amoenom were tested on the A. baumanii isolates from clinical samples of burn wounds.
Methods: 30 multi-drug resistant A. baumannii strains, which were isolated from burn wounds at Motahari Hospital of Tehran, were selected. The plants were purchased from a famous Atari in Tehran in 2013 and the methanolic extract was prepared by Peculator apparatus. Antibacterial activity of the methanolic extract was evaluated by disc diffusion method based on CLSI protocol 2012.
Results: The mean of diameter of the inhibition zone for different concentrations of extract were; 9.967±6.139 mm at 4000 ppm, 13.37±5.45 mm at the 400 ppm, 13.53±5.49 mm at the 200 ppm, 14.77±5.17mm at the 100 ppm and 14.13±5.7806 mm at the concentration of 50 ppm.
Conclusion: Clinical strains of the A. baumannii were almost highly resistant to imipenem which is the common choice of antibiotic therapy in hospitals. Due to the calculated p value
£0.05 in this study, we can say that borage extract can be as good as or even better than the imipenem which is used in hospitals recently.

 
Keyword(s): ACINETOBACTER BAUMANNII, ECHIUM AMOENUM FISCH
 
References: 
  • ندارد
 
  Yearly Visit 35
 
Latest on Blog
Enter SID Blog