Paper Information

Journal:   IRANIAN JOURNAL OF PUBLIC HEALTH   AUGUST 2014 , Volume 43 , Number SUPPLEMENT 2; Page(s) 32 To 32.
 
Paper: 

CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF ESSENTIAL OIL FROM (ROSMARINUS OFFICINALIS) AND (MENTHA SPICATA) AGAINST ORAL PATHOGENS

 
 
Author(s):  ROOMIANI LALEH*, ROOMIANI MEHRI
 
* DEPARTMENT OF FISHERIES, KHOUZESTAN SCIENCE AND RESEARCH BRANCH, ISLAMIC AZAD UNIVERSITY, AHVAZ, IRAN
 
Abstract: 

Background: The microorganisms evaluated in this study are considered risk factors for oral diseases such as caries and periodontitis; they can also reach the bloodstream triggering other diseases in the human body, like endocarditis, brain abscesses, throat infections, respiratory and gastrointestinal system infections and bacteremia. Thus, this study carried out for antibacterial activity of essential oil from R. officinalis and M. spicata against some oral pathogens; Streptococcus mutans and Streptococcus sobrinus.
Methods: The chemical composition of the essential oils from leaves R. officinalis and M. spicata was determined by gas chromatography (GC) and gas chromatography–mass spectrometry (GC-MS). Antibacterial activity of the essential oils of plants were determined in triplicate by using the microdilution broth method in 96-well.
Results: Carvon, Limonene and Menthone in leaf of M. spicata and 1, 8- cineol and alpha-pinene in leaf R. officinalis were the major components. The oils from R. officinalis and M. spicata leaves showed high antimicrobial activity, with minimum inhibitory concentrations 125
mg/mL for the tested bacteria, including S. mutans and S. sobrinus. But for M. spicata , minimum inhibitory concentrations were determined 65 and 125 ?g/mL for S.mutans and S. sobrinus.
Conclusion: The essential oils of R. officinalis and M. spicata leaves have shown promising activity against oral pathogens. Our results indicated that some active components are present in oils, so this makes them particularly interesting for future studies and development of novel antimicrobial agents.

 
Keyword(s): ROSMARINUS OFFICINALIS, MENTHA SPICATA, ORAL PATHOGENS
 
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