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Paper Information

Journal:   ACTA MEDICA IRANICA   2014 , Volume 52 , Number 7; Page(s) 496 To 504.
 
Paper: 

MELATONIN IMPROVE THE SPERM QUALITY IN FORCED SWIMMING TEST INDUCED OXIDATIVE STRESS IN NANDROLONE TREATED WISTAR RATS

 
 
Author(s):  MINAII BAGHER, MOAYERI ARDESHIR, SHOKRI SAEED*, HABIBI ROUDKENAR MEHRYAR, GOLMOHAMMADI TAGHI, MALEK FATEMEH, BARBARESTANI MOHAMMAD
 
* DEPARTMENT OF ANATOMY, FACULTY OF MEDICINE, ZANJAN UNIVERSITY OF MEDICAL SCIENCES, ZANJAN, IRAN
 
Abstract: 

This study investigates the effects of melatonin on the sperm quality and testis weight after the combination of swimming exercise and nandrolone decanoate (DECA). Two groups of male Wistar rats were treated for eight weeks as follows; group A consist of CO (control), Sham, N (DECA), S (swimming) and NS (DECA plus swimming); and group B: Sham M (sham melatonin), M (melatonin), MN (melatonin plus DECA), MS (melatonin plus swimming), MNS (melatonin, DECA plus swimming). The motility of sperm was significantly improved in melatonin groups in comparison to N, S and NS groups (P£0.05). The left testes weight was decreased in N, NS and MNS groups, and the right testes weight was decreased in N, S, NS, MS and MNS groups in compare with the control group. This study concluded that melatonin probably could improve the sperm motility and sex organs weight after the combination of DECA and exercise.

 
Keyword(s): MELATONIN, NANDROLONE DECANOATE, SWIMMING, TESTIS, RAT
 
References: 
 
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