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Paper Information

Journal:   IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)   2014 , Volume 13 , Number 4; Page(s) 1403 To 1407.
 
Paper: 

STRUCTURAL CHARACTERISATION OF A POLYSACCHARIDE FROM RADIX RANUNCULUS TERNATI

 
 
Author(s):  HUANG XUEFENG, ZHAO YUN*, JIN XIN
 
* MEDICAL COLLEGE OF XIAMEN UNIVERSITY, XIANGAN DISTRICT, XIAMEN 361000, CHINA
 
Abstract: 

A water soluble polysaccharide, HB-1, with a molecular weight of 23, 930, was isolated from radix Ranunculi ternati. by hot water extraction, ethanol precipitation, deproteination, ultrafiltration and gel-filtration column chromatography. Its sugar composition was determined by GLC as Glc, Ara, and Gal in a molar ration of 16.071: 2.722: 1. And the absolute configuration of Glc was identified as D. Smith degradation and methylation reaction showed the proportion of -1Glc (A) was about 16%, -1Glc4- (B) about 62%, Ara14 2 (C) about 14%, and -1Gal6- (D) about 8%. The repetitive unit was likely composed of 3 As, 3 Cs, 13 Bs and 1 D. Together with the average molecular weight, it was predictable that HB-1 consisted of about seven of the repetitive unit. The inhibition activity of HB-1 on human glioma cell line SF188 was also measured, only to find it inactive.

 
Keyword(s): RANUNCULUS TERNATUS THUNB, POLYSACCHARIDE, ULTRAFILTRATION, ABSOLUTE CONFIGURATION, SMITH DEGRADATION, METHYLATION REACTION, ANTI-TUMOR ACTIVITY
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

HUANG, X., & ZHAO, Y., & JIN, X. (2014). STRUCTURAL CHARACTERISATION OF A POLYSACCHARIDE FROM RADIX RANUNCULUS TERNATI. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 13(4), 1403-1407. https://www.sid.ir/en/journal/ViewPaper.aspx?id=409672



Vancouver: Copy

HUANG XUEFENG, ZHAO YUN, JIN XIN. STRUCTURAL CHARACTERISATION OF A POLYSACCHARIDE FROM RADIX RANUNCULUS TERNATI. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR). 2014 [cited 2021November28];13(4):1403-1407. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=409672



IEEE: Copy

HUANG, X., ZHAO, Y., JIN, X., 2014. STRUCTURAL CHARACTERISATION OF A POLYSACCHARIDE FROM RADIX RANUNCULUS TERNATI. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), [online] 13(4), pp.1403-1407. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=409672.



 
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