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Journal:   ANESTHESIOLOGY AND PAIN MEDICINE   OCTOBER 2014 , Volume 4 , Number 4; Page(s) 0 To 0.
 
Paper: 

Comparing The Effects Of Morphine Sulfate And Diclofenac Suppositories On Postoperative Pain In Coronary Artery Bypass Graft Patients

 
 
Author(s):  Imantalab Vali, Mirmansouri Ali*, Sedighinejad Abbas, Naderi Nabi Bahram, Farzi Farnoush, Atamanesh Hadi, Nassiri Nassir
 
* ANESTHESIA RESEARCH CENTER, DR. HESHMAT HOSPITAL, GUILAN UNIVERSITY OF MEDICAL SCIENCES, RASHT, IRAN
 
Abstract: 
Background: Simple and efficient way of pain management after Coronary Artery Bypass Graft (CABG) surgery is an important aspect of patients’ care.Objectives: This study aimed to compare the effects of morphine and diclofenac suppositories on postoperative pain management.Patients and Methods: In this double-blinded clinical trial study, 120 patients aged 30-65 years old, undergone CABG, were equally divided into two groups of A (morphine) and B (diclofenac). All patients were anesthetized with intravenous fentanyl 10 mg/kg, etomidate 0.2 mg/kg and cisatracurium 0.2 mg/kg. Anesthesia was maintained with oxygen 50% and air 50%, propofol 50 mg/kg/min, fentanyl 1-2 mg/kg/h and atracurium 0.6 mg/kg/h. Analgesics were administered after the operation at intensive care unit (ICU) and Visual Analogue Score (VAS) was evaluated in both groups in 4-hour intervals after extubation for 24 hours. After extubation in case of VAS>3, morphine suppository 10 mg (group A) or diclofenac suppository 50 mg (group B) was administered for patients.Results: No significant statistical relationship was found between the two groups regarding gender, age, BMI, paracetamol consumption, length of operation time, cardiopulmonary bypass pump (CPB) time, and stay time at ICU (P Value³0.05). Total dosage of used morphine was 22±8.3 mg in each patient and total dosage of used diclofenac was 94±32.01 mg. Average variation of VAS at measured intervals was significant (P Value£0.0001), but these variations were not significantly different when comparing the two groups (P Value=0.023).Conclusions: Both morphine and diclofenac suppositories reduced pain significantly and similarly after CABG surgery.
 
Keyword(s): CARDIAC SURGERY, PAIN, MORPHINE, DICLOFENAC
 
 
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APA: Copy

IMANTALAB, V., & MIRMANSOURI, A., & SEDIGHINEJAD, A., & NADERI NABI, B., & FARZI, F., & ATAMANESH, H., & NASSIRI, N. (2014). COMPARING THE EFFECTS OF MORPHINE SULFATE AND DICLOFENAC SUPPOSITORIES ON POSTOPERATIVE PAIN IN CORONARY ARTERY BYPASS GRAFT PATIENTS. ANESTHESIOLOGY AND PAIN MEDICINE, 4(4), 0-0. https://www.sid.ir/en/journal/ViewPaper.aspx?id=409666



Vancouver: Copy

IMANTALAB VALI, MIRMANSOURI ALI, SEDIGHINEJAD ABBAS, NADERI NABI BAHRAM, FARZI FARNOUSH, ATAMANESH HADI, NASSIRI NASSIR. COMPARING THE EFFECTS OF MORPHINE SULFATE AND DICLOFENAC SUPPOSITORIES ON POSTOPERATIVE PAIN IN CORONARY ARTERY BYPASS GRAFT PATIENTS. ANESTHESIOLOGY AND PAIN MEDICINE. 2014 [cited 2022June30];4(4):0-0. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=409666



IEEE: Copy

IMANTALAB, V., MIRMANSOURI, A., SEDIGHINEJAD, A., NADERI NABI, B., FARZI, F., ATAMANESH, H., NASSIRI, N., 2014. COMPARING THE EFFECTS OF MORPHINE SULFATE AND DICLOFENAC SUPPOSITORIES ON POSTOPERATIVE PAIN IN CORONARY ARTERY BYPASS GRAFT PATIENTS. ANESTHESIOLOGY AND PAIN MEDICINE, [online] 4(4), pp.0-0. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=409666.



 
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