Paper Information

Journal:   ANESTHESIOLOGY AND PAIN MEDICINE   OCTOBER 2014 , Volume 4 , Number 4; Page(s) 0 To 0.
 
Paper: 

INCIDENCE AND PREDISPOSING FACTORS OF COGNITIVE DISORDERS FOLLOWING OFF-PUMP CORONARY ARTERY BYPASSES GRAFT SURGERY

 
 
Author(s):  JOUDI MARJAN, FATHI MEHDI*, HARATI HADI, JOUDI MITRA, IZANLOO AZRA, RAHDARI ALI, SOLTANI GHASEM
 
* DEPARTMENT OF ANESTHESIOLOGY, FACULTY OF MEDICINE, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, MASHHAD, IRAN
 
Abstract: 

Background: Cognitive disorder, which is a common problem for the hospitalized patients, is a fluctuating cognitive destruction that leads to the loss of consciousness. It is usually accompanied by increased mortality, prolonged hospital stay, and decreased rehabilitation.
Objectives: The purpose of this study was to determine the risk factors associated with cognitive disorder after coronary artery bypasses graft surgery (CABG).
Patients and Methods: A total of 171 patients who had undergone off-pump CABG without any history of psychiatric disorders were enrolled. Samples were selected according to a purposive sampling method. The Mini-Mental State Examination (MMSE) questionnaire was given to each patients to assess the incidence of cognitive disorder during the first 24 hours of surgery in ICU. To compare creatinine, erythrocytes sedimentation rate, extubation time, and patients’ age between those with and those without postoperative cognitive disorder, independent-samplest test was employed. To compare two groups in terms of any history of diseases such as diabetes, hypertension, and hyperlipidemia, and qualitative C-reactive protein (CRP), Chi square test was used.
Results: Results showed that 75% of patients had postoperative cognitive disorder. There was a significant association between the history of hypertension, CRP, and preoperative creatinine levels in both cognitive disorder and control groups.
Conclusions: Given the significant prevalence of postoperative cognitive disorder and significant association between the history of hypertension, CRP, and preoperative creatinine and cognitive disorder, the detection of patient’s clinical symptoms may improve diagnosis, treatment, and even prevention of cognitive disorder.

 
Keyword(s): OFF-PUMP CORONARY ARTERY BYPASS, COGNITIVE DISORDER, DELIRIUM, RISK FACTORS
 
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