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Paper Information

Journal:   JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)   MARCH 2014 , Volume 19 , Number SUPPLEMENT 1; Page(s) 67 To 70.
 
Paper: 

DETECTION OF COLISTIN SENSITIVITY IN CLINICAL ISOLATES OF ACINETOBACTER BAUMANNII IN IRAN

 
 
Author(s):  VAKILI BAHAREH, FAZELI HOSSEIN, SHOAEI PARISA, YARAN MAJID, ATAEI BEHROOZ, KHORVASH FARZIN*, KHALEGHI MOJ
 
* NOSOCOMIAL INFECTION RESEARCH CENTER, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

Background: Nosocomial infection caused by Acinetobacter baumannii has emerged as a serious problem world-wide. Finding the suitable drug is an important priority. The aim of this study was to determine colistin (polymyxin E) resistance in clinical isolates of A. baumannii from intensive care units (ICUs) of Al Zahra Hospital.
Materials and Methods: Sixty isolates of A. baumannii from patients hospitalized in ICU (Al Zahra Hospital, Isfahan University of Medical Sciences [IUMS]) were studied. All isolates of A. baumannii were tested for colistin susceptibility by Eopsilometer test (E-test). Results: Of the 60 isolates 57, (95%) were multidrug resistant (MDR) and 76.6% (46.60) were highly resistant. The rate of colistin resistant with the E-test method was 11.6% (7.60). Conclusion: As the frequency of resistance to colistin is low, it can be used as an easily available drug for treatment of MDR A. baumannii strains, which are susceptible to colistin.

 
Keyword(s): ACINETOBACTER BAUMANNII, COLISTIN RESISTANCE, MULTIDRUG RESISTANT ORGANISM
 
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