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Paper Information

Journal:   RESEARCH JOURNAL OF PHARMACOGNOSY   2014 , Volume 1 , Number 4; Page(s) 19 To 25.
 
Paper: 

CYTOTOXIC ACTIVITY SCREENING OF SOME MEDICINAL PLANTS FROM SOUTH OF IRAN

 
 
Author(s):  ESMAEILI S., HAMZELOO MOGHADAM M., GHAFFARI S., MOSADDEGH M.*
 
* DEPARTMENT OF TRADITIONAL PHARMACY, SCHOOL OF TRADITIONAL MEDICINE, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Background and objectives: Cancer is a public health problem all over the world. Herbal medicines have a vital role in the prevention and treatment of cancer and large numbers of plants and their isolated constituents have shown potential anticancer activity.
Methods: Twenty seven medicinal plants from southern Iran provinces have been extracted with methanol and screened for their cytotoxic activity against MCF-7, WEHI-164, HepG-2, MDBK and A-549 cell lines by MTT assay.
Results: The methanol extracts of two species, Calotropis procera and Juniperus excelsa, demonstrated to be more effective compared to other extracts.
Conclusion: The above species are proper candidates for further cancer studies.

 
Keyword(s): CYTOTOXIC ACTIVITY, IRAN, MEDICINAL PLANTS, MTT ASSAY
 
References: 
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