Paper Information

Journal:   ARCHIVES OF IRANIAN MEDICINE   FEBRUARY 2013 , Volume 16 , Number 2; Page(s) 123 To 125.
 
Paper: 

NEUROENDOCRINE TUMOR OF THE GALLBLADDER

 
DOI: 

013162/AIM.0014

 
Author(s):  ELAHI FAZEL, AHMADZADEH AHMAD*, YADOLLAHZADEH MAHDI, HASSANPOUR KIANA, BABAEI MOHAMMADREZA
 
* HEMATOLOGY WARD, AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCE, GOLESTAN HOSPITAL, AHVAZ, IRAN
 
Abstract: 

Neuroendocrine tumors (NET) arise from neuroendocrine cells and are an exceedingly rare malignancy in the gallbladder. In this case report, a 52-year-old woman with complaints of episodic abdominal pain for two months prior was admitted to our hospital. She had no other signs and symptoms and her laboratory tests were within normal limits. Ultrasonography showed a broad-necked mass (26×12 mm) in the gallbladder for which she underwent laparoscopic cholecystectomy. The final pathological diagnosis was a high grade neuroendocrine carcinoma of the gallbladder with involvement of the lymph nodes and omentum. The patient received the chemotherapy regimens of gemcitabine plus cisplatin, followed by docetaxel plus sunitinib for her metastatic liver lesions. She also underwent radiofrequency ablation. Serial CT-scans revealed metastatic liver lesions that had decreased in size, with no significant improvement. The patient refused additional treatment and at 46 months, she was doing well with no complaints of any pain, disease recurrence, or metastatic progression.

 
Keyword(s): CASE REPORT, CHEMOTHERAPY, GALLBLADDER, NEUROENDOCRINE TUMOR, RADIOFREQUENCY ABLATION
 
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