Paper Information

Journal:   IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)   2014 , Volume 13 , Number 3; Page(s) 1049 To 1054.
 
Paper: 

PHYTOCHEMICAL INVESTIGATIONS ON CHEMICAL CONSTITUENTS OF ACHILLEA TENUIFOLIA LAM

 
 
Author(s):  MORADKHANI SHIRIN*, KOBARFARD FARZAD, AYATOLLAHI SEYED ABDOL MAJID
 
* DEPARTMENT OF PHARMACOGNOSY AND BIOTECHNOLOGY, SCHOOL OF PHARMACY, HAMADAN UNIVERSITY OF MEDICAL SCIENCES, HAMADAN, IRAN
 
Abstract: 

Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’, 4’, 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (b- sitosterol 3-O- b- D- glucopyranoside, compound 5), 2, 4- dihydroxy methyl benzoate (compound 6) were isolated for the first time. The structure of isolated compounds was elucidated by means of different spectroscopic methods such as UV, IR, Mass and 1H- NMR (1D and 2D) and 13C-NMR. For further confirming the structures of isolated compounds, comparison of the spectral data of them with those reported in the litratures have been done.

 
Keyword(s): ACHILLEA TENUIFOLIA, ASTERACEAE, EUPATORINE, LUPEOL, DAUCOSTEROL
 
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