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Paper Information

Journal:   IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)   2013 , Volume 7 , Number 4 (SUPPL.1); Page(s) 18 To 19.
 
Paper: 

LEIGH DISEASE

 
 
Author(s):  SALEHPOUR SHADAB*
 
* GENOMIC RESEARCH CENTER, LOGHMAN HOSPITAL, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Introduction: Leigh disease is an inherited early-onset progressive neurodegenerative/ neurometabolic disorder with a characteristic neuropathology consisting of focal, bilateral lesions in one or more areas of the central nervous system, including the brainstem, thalamus, basal ganglia, cerebellum, and spinal cord. The lesions are areas of demyelination, gliosis, necrosis, spongiosis, or capillary proliferation.

 
Keyword(s): LEIGH DISEASE, MITOCHONDROPATHY, NEUROMETABOLIC, NEURODEGENERATIVE
 
References: 
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