Paper Information

Journal:   IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)   SPRING 2014 , Volume 8 , Number 2; Page(s) 1 To 10.
 
Paper: 

POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME IN PEDIATRIC HEMATOLOGIC- ONCOLOGIC DISEASE: LITERATURE REVIEW AND CASE PRESENTATION; REVIEW ARTICLE

 
 
Author(s):  ARZANIAN MOHAMMAD THAGHI, SHAHIN SHAMSIAN BIBI*, KARIMZADEH PARVANEH, KAJIYAZDI MOHAMMAD, MALEK FATIMA, HAMMOUD MOHAMMAD
 
* SHARIATI AVE, MOFID CHILDREN HOSPITAL, TEHRAN, IRAN
 
Abstract: 

Objective: Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological disease entity, which is represented by characteristic magnetic resonance imaging (MRI) findings of subcortical/cortical hyperintensity in T2-weighted sequences. It is more often seen in parietaloccipital lobes, and is accompanied by clinical neurological changes. PRES is a rare central nervous system (CNS) complication in patients with childhood hematologic-oncologic disese and shows very different neurological symptoms between patients, ranging from numbness of extremities to generalized seizure. In this article, we will review PRES presentation in hematologic-oncologic patients. Then, we will present our patient, a 7-year-old boy with Evans syndrome on treatment with cyclosporine, mycophenolate mofetil (MMF) and prednisone, with seizure episodes and MRI finding in favour of PRES.

 
Keyword(s): POSTERIOR REVERSIBLE ENCEPHALOPATY SYNDROME (PRES), HEMATOLOGIC DISEASE, LEUKEMIA, CYCLOSPORINE
 
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