Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   BASIC AND CLINICAL NEUROSCIENCE   SPRING 2014 , Volume 5 , Number 2; Page(s) 162 To 168.
 
Paper: 

EFFECTS OF HYDROALCOHOLIC EXTRACT OF TANACETUM SONBOLII (ASTERACEAE) ON PAIN-RELATED BEHAVIORS DURING FORMALIN TEST IN MICE

 
 
Author(s):  SOFIABADI MOHAMMAD, AZHDARI ZARMEHRI HASSAN*, NADERI FIROUZEH, GHALANDARI SHAMAMI MOHADESEH, SONBOLI ALI, HAGHPARAST ABBAS
 
* DEPARTMENT OF BASIC SCIENCES, TORBAT HEYDARIYEH UNIVERSITY OF MEDICAL SCIENCES, TORBAT HEYDARIYEH, IRAN
 
Abstract: 

Introduction: Tanacetum sonbolii (Asteraceae) is an endemic species in Iran. In the present study, we examined the effects of Tanacetum sonbolii hydroalcoholic extract on the formalin test in mice.
Methods: 126 Swiss albino mice weighing 230-280g were used as subjects. The formalin test was performed on two control groups (marked as intact and saline groups; n=6 in each group) and an experimental group. In all groups, the formalin test was recorded for 60 min after administration of extract and drugs in mice.
Results: The results showed that Tanacetum sonbolii (150 and 300 mg/kg) produced significant antinociception in phase 2. In addition, different doses of Tanacetum sonbolii extract (600, 900 and 1200 mg/kg) also induced antinociceptive effects in phase1 and phase 2. On the other hand, morphine could induce antinociception in a dose-dependent manner. Diclofenac (10 mg/ kg) failed to affect the pain scores compared to Tanacetum sonbolii (300 mg/kg) group.
Discussion: It seems that administration of hydroalcoholic extract of Tanacetum sonbolii has the potential to relieve pain through both central and peripheral mechanisms in persistent inflammatory nociception.

 
Keyword(s): TANACETUM SONBOLII (ASTERACEAE), MORPHINE, FORMALIN TEST, MICE
 
 
References: 
  • Not Registered.
  •  
  •  
 
Citations: 
  • Not Registered.
 
+ Click to Cite.
APA: Copy

SOFIABADI, M., & AZHDARI ZARMEHRI, H., & NADERI, F., & GHALANDARI SHAMAMI, M., & SONBOLI, A., & HAGHPARAST, A. (2014). EFFECTS OF HYDROALCOHOLIC EXTRACT OF TANACETUM SONBOLII (ASTERACEAE) ON PAIN-RELATED BEHAVIORS DURING FORMALIN TEST IN MICE. BASIC AND CLINICAL NEUROSCIENCE, 5(2), 162-168. https://www.sid.ir/en/journal/ViewPaper.aspx?id=408786



Vancouver: Copy

SOFIABADI MOHAMMAD, AZHDARI ZARMEHRI HASSAN, NADERI FIROUZEH, GHALANDARI SHAMAMI MOHADESEH, SONBOLI ALI, HAGHPARAST ABBAS. EFFECTS OF HYDROALCOHOLIC EXTRACT OF TANACETUM SONBOLII (ASTERACEAE) ON PAIN-RELATED BEHAVIORS DURING FORMALIN TEST IN MICE. BASIC AND CLINICAL NEUROSCIENCE. 2014 [cited 2021November30];5(2):162-168. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408786



IEEE: Copy

SOFIABADI, M., AZHDARI ZARMEHRI, H., NADERI, F., GHALANDARI SHAMAMI, M., SONBOLI, A., HAGHPARAST, A., 2014. EFFECTS OF HYDROALCOHOLIC EXTRACT OF TANACETUM SONBOLII (ASTERACEAE) ON PAIN-RELATED BEHAVIORS DURING FORMALIN TEST IN MICE. BASIC AND CLINICAL NEUROSCIENCE, [online] 5(2), pp.162-168. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408786.



 
  pdf-File
Yearly Visit 48
 
 
Latest on Blog
Enter SID Blog