About 85% of rural population in India depends on groundwater for their domestic needs. Fluoride is a naturally occurring element found in groundwater of various regions of the world. High concentration of fluoride in drinking water may result in fluorosis. The disease is characterized by discolored and mottled teeth (dental fluorosis) or by permanent bone and joint damage (skeletal fluorosis). The fluoride-related problems are closely associated with climate; in tropical regions, people consume more water and are at a higher risk of fluorosis.