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Paper Information

Journal:   JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)   JUNE 2014 , Volume 19 , Number 6; Page(s) 567 To 570.
 
Paper: 

DETECTION OF QUINOLONE-RESISTANCE MUTATIONS OF PARC GENE IN CLINICAL ISOLATES OF ACINETOBACTER BAUMANNII IN IRAN (SHORT COMMUNICATION)

 
 
Author(s):  VAKILI BAHAREH, KHORVASH FARZIN, FAZELI HOSSEIN*, KHALEGHI MOJ
 
* INFECTIOUS DISEASES AND TROPICAL MEDICINE RESEARCH CANTER, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 
Background: The purpose of this study was to screen of parC gene mutations in clinical isolates of Acinetobacter baumannii from intensive care units (ICUs) of Alzahra Hospital, Isfahan, Iran.Materials and Methods: Seventy isolates of A. baumannii between March 2011 and June 2012 were studied. Susceptibility test was established by E-test method. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and sequencing was performed for detection of parC gene mutation.Results: 77.1% of specimens were highly resistant. Mutation at position 80 in parC was observed in 93% of isolates.Conclusion: High proportion of A. baumannii isolates had a mutation in parC that can play an important role in increased incidence of these isolates.
 
Keyword(s): A. BAUMANNII, MULTIDRUG RESISTANT, PARC GENE
 
 
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Citations: 
 
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APA: Copy

VAKILI, B., & KHORVASH, F., & FAZELI, H., & KHALEGHI, M. (2014). DETECTION OF QUINOLONE-RESISTANCE MUTATIONS OF PARC GENE IN CLINICAL ISOLATES OF ACINETOBACTER BAUMANNII IN IRAN (SHORT COMMUNICATION). JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 19(6), 567-570. https://www.sid.ir/en/journal/ViewPaper.aspx?id=408638



Vancouver: Copy

VAKILI BAHAREH, KHORVASH FARZIN, FAZELI HOSSEIN, KHALEGHI MOJ. DETECTION OF QUINOLONE-RESISTANCE MUTATIONS OF PARC GENE IN CLINICAL ISOLATES OF ACINETOBACTER BAUMANNII IN IRAN (SHORT COMMUNICATION). JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS). 2014 [cited 2021December02];19(6):567-570. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408638



IEEE: Copy

VAKILI, B., KHORVASH, F., FAZELI, H., KHALEGHI, M., 2014. DETECTION OF QUINOLONE-RESISTANCE MUTATIONS OF PARC GENE IN CLINICAL ISOLATES OF ACINETOBACTER BAUMANNII IN IRAN (SHORT COMMUNICATION). JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), [online] 19(6), pp.567-570. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408638.



 
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