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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   JUNE 2014 , Volume 12 , Number 6; Page(s) 389 To 394.
 
Paper: 

EXPRESSION OF TOLL-LIKE RECEPTORS 7-10 IN HUMAN FALLOPIAN TUBES

 
 
Author(s):  GHASEMI NASRIN, AMJADI FATEME SADAT, SALEHI ENSIEH, SHAKERI MOJGAN, AFLATOONIAN ABBAS*, AFLATOONIAN REZA*
 
* NO 12, EASTERN HAFEZ ST., BANI HASHEM ST., RESALAT HIGHWAY, TEHRAN, IRAN
 
Abstract: 

Background: The human female reproductive tract (FRT) is constantly deal with the invading pathogens. Recognition of these pathogens is attributed to the family of Toll like receptors (TLR) as a major part of the innate immune system. We and others have previously revealed that TLRs1-6 express in the female reproductive tract. However, more studies should be done to detect TLRs 7-10 in the female reproductive tract, especially in the fallopian tubes.
Objective: To examine the expression of TLRs7-10 in human fallopian tube tissue.
Materials and Methods: Using immunostaining techniques, distribution of TLR7-10 was studied in surgical sections from the uterine tubes, obtained from patients undergoing tubal ligation and hysterectomy for benign gynecological conditions. RT-PCR was used to show the existence of TLR7-10 genes in fallopian tube tissue.
Results: TLR7-10 proteins were detected in the fallopian tube epithelium, although the intensity of staining was not equal in cases. TLR7-10 genes were expressed in human fallopian tube tissue.
Conclusion: This study indicates that TLR7-10 is expressed in fallopian tubes tissues, and may play an important role in microbial recognition, and in host defense against ascending infection.

 
Keyword(s): FALLOPIAN TUBE, INNATE IMMUNITY, TOLL LIKE RECEPTORS (TLRS), REPRODUCTIVE MEDICINE
 
 
References: 
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Click to Cite.
APA: Copy

GHASEMI, N., & AMJADI, F., & SALEHI, E., & SHAKERI, M., & AFLATOONIAN, A., & AFLATOONIAN, R. (2014). EXPRESSION OF TOLL-LIKE RECEPTORS 7-10 IN HUMAN FALLOPIAN TUBES. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 12(6), 389-394. https://www.sid.ir/en/journal/ViewPaper.aspx?id=408180



Vancouver: Copy

GHASEMI NASRIN, AMJADI FATEME SADAT, SALEHI ENSIEH, SHAKERI MOJGAN, AFLATOONIAN ABBAS, AFLATOONIAN REZA. EXPRESSION OF TOLL-LIKE RECEPTORS 7-10 IN HUMAN FALLOPIAN TUBES. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE). 2014 [cited 2021May15];12(6):389-394. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408180



IEEE: Copy

GHASEMI, N., AMJADI, F., SALEHI, E., SHAKERI, M., AFLATOONIAN, A., AFLATOONIAN, R., 2014. EXPRESSION OF TOLL-LIKE RECEPTORS 7-10 IN HUMAN FALLOPIAN TUBES. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), [online] 12(6), pp.389-394. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408180.



 
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