Paper Information

Journal:   INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE   2014 , Volume 5 , Number 3; Page(s) 287 To 292.
 
Paper: 

SEROPREVALENCE OF RUBELLA IGG ANTIBODY IN PREGNANT WOMEN IN OSOGBO, NIGERIA

 
 
Author(s):  OLATUNJI MATHEW KOLAWOLE*, ANJORIN EKUNTOYE O., ADEKANLE DANIEL A., KOLAWOLE CAROLINE FOLASHADE, DUROWADE KABIR ADEKUNLE
 
* DEPARTMENT OF MICROBIOLOGY, INFECTIOUS DISEASES AND ENVIRONMENTAL HEALTH RESEARCH GROUP, UNIVERSITY OF ILORIN, ILORIN, KWARA STATE, NIGERIA
 
Abstract: 

Background: Infection of mothers with Rubella virus during pregnancy can be serious; if the mother is infected within the first 20 weeks of pregnancy she is likely to have miscarriage, stillbirth, or baby with congenital rubella syndrome. This study was carried out to define Rubella virus seroprevalence in pregnancy in Osogbo, Nigeria.
Methods: This study is a cross-sectional sero-survey of rubella IgG antibody among pregnant women attending antenatal clinic of Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Nigeria. Socio-demographic information on participants was collected by interviewer-administered questionnaire while venous samples were collected, stored at ?20oC and serum samples were screened for detection of rubella IgG antibodies using the enzyme linked immunosorbent assay.
Results: Of the 200 sample evaluated for rubella Immunoglobulin G antibody, 175 (87.5%) were positive and 25 (12.5%) were negative. The result indicated prevalence of 85.7% in 15-19 year age group, 86.8% in 20-24 year age group, 89.6% in 25-29 year group, and 100% in greater than 40 year age group. Rubella IgG seroprevalence was not associated with age, gestational age, gravidity, vaccination, occupation and education.
Conclusions: As the immunity gap in the studied population was high, rubella vaccination should be provided for all women of child-bearing age and children.

 
Keyword(s): IGG ANTIBODY, NIGERIA, PREGNANT WOMEN, RUBELLA
 
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