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Paper Information

Journal:   INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)   JULY 2014 , Volume 12 , Number 3; Page(s) 1 To 6.
 
Paper: 

PREDICTORS OF ACUTE KIDNEY INJURY IN GERIATRIC PATIENTS UNDERGOING TOTAL KNEE REPLACEMENT SURGERY

 
 
Author(s):  SEHGAL VISHAL, SINGH BAJWA SUKHMINDER JIT*, SEHGAL RINKU, EAGAN JEREMIAH, REDDY PRAVEEN, LESKO SAMUEL M.
 
* DEPARTMENT OF ANESTHESIOLOGY AND INTENSIVE CARE MEDICINE, GIAN SAGAR MEDICAL COLLEGE, BANUR, PATIALA, PUNJAB, INDIA
 
Abstract: 

Background: Few studies have focused on patients’ characteristics that affects acute kidney injury (AKI) after total knee replacement surgery (TKR).
Objectives: The primary objective of this retrospective study was to identify patients’ characteristics associated with AKI after TKR.
Patients and Methods: Between January 2008 and December 2009, 659 patients with a mean age of 67.1 years (range, 39-99) underwent TKA at Regional Hospital Knee and Hip Institute. Retrospective chart review was done to identify patients’ characteristics that were associated with AKI after TKR. Logistic regression was used to evaluate AKI.
Results: AKI occurred in 21.9% of patients. AKI risk decreased between 2008 and 2009 (odds ratio, 0.55, 95% CI, -0.37 to 0.82) but increased with age (P<0.001), diabetes mellitus (DM), and angiotensin converting enzyme inhibitors (ACEI) /angiotensin receptor blockers (ARB) use (OR, -1.6, 95% CI, -1.0 to 2.5, and OR, -1.5, 95% CI, -1.0 to 2.3, respectively). However, the effects of DM and ACEI/ARB use were not independent, when both were included in the regression model, neither was statistically significant, and both ORs were smaller than combined OR.
Conclusions: When examined separately, both DM and preoperative ACEI/ARB use increased the risk of AKI, however these factors were correlated and were not independent predictors of significantly increased risk. Patients with DM have higher tendency to develop AKI and hence, preoperative renal risk stratification should be done in all patients with DM.

 
Keyword(s): ACUTE KIDNEY INJURY, GERIATRICS, CHRONIC KIDNEY DISEASE, DIABETES MELLITUS, TOTAL KNEE REPLACEMENT, HEALTH CARE REFORM
 
 
References: 
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Click to Cite.
APA: Copy

SEHGAL, V., & SINGH BAJWA, S., & SEHGAL, R., & EAGAN, J., & REDDY, P., & LESKO, S. (2014). PREDICTORS OF ACUTE KIDNEY INJURY IN GERIATRIC PATIENTS UNDERGOING TOTAL KNEE REPLACEMENT SURGERY. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 12(3), 1-6. https://www.sid.ir/en/journal/ViewPaper.aspx?id=408100



Vancouver: Copy

SEHGAL VISHAL, SINGH BAJWA SUKHMINDER JIT, SEHGAL RINKU, EAGAN JEREMIAH, REDDY PRAVEEN, LESKO SAMUEL M.. PREDICTORS OF ACUTE KIDNEY INJURY IN GERIATRIC PATIENTS UNDERGOING TOTAL KNEE REPLACEMENT SURGERY. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM). 2014 [cited 2021May12];12(3):1-6. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408100



IEEE: Copy

SEHGAL, V., SINGH BAJWA, S., SEHGAL, R., EAGAN, J., REDDY, P., LESKO, S., 2014. PREDICTORS OF ACUTE KIDNEY INJURY IN GERIATRIC PATIENTS UNDERGOING TOTAL KNEE REPLACEMENT SURGERY. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), [online] 12(3), pp.1-6. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=408100.



 
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