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Paper Information

Journal:   JOURNAL OF CHEMICAL HEALTH RISKS (JCHR)   2014 , Volume 4 , Number 4; Page(s) 9 To 16.
 
Paper: 

CHARACTERIZATION OF CHEMICAL COMPOSITION AND ANTIOXIDANT PROPERTIES OF TRACHYSPERMUM AMMI SEED AS A POTENTIAL MEDICINAL PLANT

 
 
Author(s):  AKHLAGHI HASHEM*, MAHDAVI BEHNAM, REZAEI HASAN
 
* DEPARTMENT OF BASIC SCIENCES, ISLAMIC AZAD UNIVERSITY, SABZEVAR BRANCH, SABZEVAR, IRAN
 
Abstract: 

In this study, the essential oil obtained by hydrodistillation of the seed of Trachyspermum ammi (Umbelliferae), growing wild in Sabzevar, Khorasan Razavi province (Iran), were analyzed by GC and GC/MS. The yield of total volatiles was 2.3% (w/w). Forty four compounds representing 91.6% of the aerial parts oil were identified. The main components of the oil were Hexadecanoic acid (27.5%), ethyl linoleate (8.5%), 6-methyl-a-ionone (8.0%), isobutyl phthalate (5.8%), a-cadinol (4.7%), germacrene D (4.3%) and ?-cadinene (3.5%). The oil was rich in nonterpenoids (56.0%). The total flavonoid content of different extracts of the plant was found to be in the range 53.2-164.5 mg/g while the maximum amount concern to methanol extract. The antioxidant activity of the extracts was also measured by radical scavenging activity of antioxidants against free radical 1, 1-diphenyl-2-picrylhydrazyl (DPPH) method. Results showed that IC50 of the extracts of Trachyspermum ammi seed are higher than the standard synthetic antioxidants, BHT, ascorbic acid and gallic acid.

 
Keyword(s): TRACHYSPERMUM AMMI, GC/MS, HEXADECANOIC ACID, ETHYL LINOLEATE, ANTIOXIDANT ACTIVITY
 
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