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Paper Information

Journal:   IRANIAN JOURNAL OF PEDIATRICS   AUGUST 2014 , Volume 24 , Number 4; Page(s) 352 To 358.
 
Paper: 

TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID

 
 
Author(s):  YAN YA MIN, FAN QIAO LING, LI AI QIU, CHEN JIA LING, DONG FEI FEI, GONG MEI*
 
* DEPARTMENT OF NURSING, SHANGHAI CHILDREN’S HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY, NO.24, LANE 1400, WEST BEIJING ROAD, SHANGHAI, CHINA
 
Abstract: 

Objective: To analyze the effects of hyaluronidase and hirudoid treatment on drug extravasation in neonates.
Methods: The medical records of 13 neonates with drug extravasation treated with hyaluronidase and hirudoid between August 1st, 2010 and May 1st, 2012 were analyzed retrospectively. The treatment procedure for drug extravasation adhered to the protocol in neonatal department. The information including age, sex, weight, diagnosis, size of affected area, site of extravasation and treatment was collected.
Findings: The extravasation injuries alleviated and the symptoms improved after treatment, no adverse drug effects were reported with use of hyaluronidase and hirudoid.
Conclusion: The treatment appeared to be beneficial in the management of extravasations of various medications in neonates and may be useful in reducing the severity of cutaneous toxicosis. However, further studies with large samples are still needed to assess the effectiveness and safety of hyaluronidase and hirudoid.

 
Keyword(s): TREATMENT, DRUG EXTRAVASATION, HYALURONIDASE, HIRUDOID, NEONATE
 
 
References: 
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Click to Cite.
APA: Copy

YAN, Y., & FAN, Q., & LI, A., & CHEN, J., & DONG, F., & GONG, M. (2014). TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID. IRANIAN JOURNAL OF PEDIATRICS, 24(4), 352-358. https://www.sid.ir/en/journal/ViewPaper.aspx?id=407984



Vancouver: Copy

YAN YA MIN, FAN QIAO LING, LI AI QIU, CHEN JIA LING, DONG FEI FEI, GONG MEI. TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID. IRANIAN JOURNAL OF PEDIATRICS. 2014 [cited 2021May06];24(4):352-358. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=407984



IEEE: Copy

YAN, Y., FAN, Q., LI, A., CHEN, J., DONG, F., GONG, M., 2014. TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID. IRANIAN JOURNAL OF PEDIATRICS, [online] 24(4), pp.352-358. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=407984.



 
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