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Journal:   JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)   4TH WEEK SEPTEMBER 2014 , Volume 32 , Number 295; Page(s) 1 To 11.
 
Paper: 

Frequency Of Mdr Acinetobacter Baumannii Isolates In Intensive Care Units (Icu) Of Isfahan Hospitals By Molecular Method And Their Antimicrobial Resistance Patterns
 
 
Author(s):  Ghajavand Hasan, Havaei Asghar, Nasr Esfahani Bahram, Fazeli Hossein, Moghim Sharareh*
 
* DEPARTMENT OF MICROBIOLOGY, SCHOOL OF MEDICINE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 
Background: Acinetobacter baumannii is one of the most important pathogen in hospital acquired infections especially in intensive care units (ICUs). This opportunistic pathogen can be easily isolated from water, soil, and hospital facilities. A.baumannii as a nosocomial opportunistic pathogen is resistant to wide range of antibiotics. The aim of this study was to determine frequency and resistance patterns of A.baumannii isolated ICUs of Isfahan Hospitals.Methods: During one year period (2012-2013), 350 specimens were collected from ICUs of Isfahan hospitals. The specimens were characterized as A .baumannii by conventional phenotypic and biochemical tests.The isolates were confirmed by PCR for OXA_51 like gene. Susceptibility of isolates was determined by standard disk diffusion method according to CLSI.Findings: From 350 specimens, 43 isolates was Acinetobacter baumannii .The antimicrobial patterns of isolates showed that 53.5% of isolates were resistant to amikacin, 83.7% to tetracyclin, 86% to ceftazidime, 90.7% to trimetoprim sulfametoxazol, 93% to imipenem, cefepime, meropenem, ampicillin -Sulbactam. All isolates were resistant to ciprofloxacin. Our findings showed that all of Acinetobacter, isolated from the ICU of Isfahan hospitals were MDR.Conclusion: This study showed a high resistant of A.baumannii to a wide range of antimicrobial agent. It is necessary to adopt appropriate strategies to control the spread of the bacteria in care unit centers and wards.
 
Keyword(s): ACINETOBACTER BAUMANNII, PCR, ANTIBIOTIC RESISTANCE, ICU
 
 
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APA: Copy

GHAJAVAND, H., & HAVAEI, A., & NASR ESFAHANI, B., & FAZELI, H., & MOGHIM, S. (2014). FREQUENCY OF MDR ACINETOBACTER BAUMANNII ISOLATES IN INTENSIVE CARE UNITS (ICU) OF ISFAHAN HOSPITALS BY MOLECULAR METHOD AND THEIR ANTIMICROBIAL RESISTANCE PATTERNS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 32(295), 1-11. https://www.sid.ir/en/journal/ViewPaper.aspx?id=407888



Vancouver: Copy

GHAJAVAND HASAN, HAVAEI ASGHAR, NASR ESFAHANI BAHRAM, FAZELI HOSSEIN, MOGHIM SHARAREH. FREQUENCY OF MDR ACINETOBACTER BAUMANNII ISOLATES IN INTENSIVE CARE UNITS (ICU) OF ISFAHAN HOSPITALS BY MOLECULAR METHOD AND THEIR ANTIMICROBIAL RESISTANCE PATTERNS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S). 2014 [cited 2022May29];32(295):1-11. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=407888



IEEE: Copy

GHAJAVAND, H., HAVAEI, A., NASR ESFAHANI, B., FAZELI, H., MOGHIM, S., 2014. FREQUENCY OF MDR ACINETOBACTER BAUMANNII ISOLATES IN INTENSIVE CARE UNITS (ICU) OF ISFAHAN HOSPITALS BY MOLECULAR METHOD AND THEIR ANTIMICROBIAL RESISTANCE PATTERNS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), [online] 32(295), pp.1-11. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=407888.
 
 
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