In this study, the forest areas of the North and North-West provinces were explored. Samples were collected from the roots, crowns, and trunks of the living trees. Samples (fungal fruiting body or the caps) were mainly of basidiomycetes and ascomycetes fungi types. The traits of each mushroom, its host, the location of the site were recorded. After the microscopic analysis of the cap, samples were investigated regarding the shape, color, thickness, the presence or absence of base, the presence or absence of upper and lower rings or both based on the type of tissue, the size, and other important characteristics. Some Species of forest medicinal fungi which according to previous research appear to have a significant impact on controlling various human diseases are introduced. It is hoped that this experiment provides a context for the cooperation of researchers and pharmacists. Some species are both edible and drug and hence cannot be directly applied. Generally speaking, the medicinal mushrooms such as Oudemansiella radicata are not edible and dangerous and should not be used as food.