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Paper Information

Journal:   JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES   FALL 2014 , Volume 16 , Number 3 (51); Page(s) 9 To 15.
 
Paper: 

EFFECT OF FOUR WEEKS OF ENDURANCE TRAINING ON SERUM LEVEL OF PARAOXONASE-1 AND LIPID PROFILE IN NON-ATHLETE OBESE MEN

 
 
Author(s):  AMOUZAD MAHDIREJEI T.*, BERAREI A.R., FARZANEGEI P., AHMADI M.
 
* ISLAMIC AZAD UNIVERSITY, SARI BRANCH, SARI, IRAN
 
Abstract: 

Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1. This study was done to determine the effect of four weeks of endurance training on serum level of Paraoxonase-1 and lipid profile in non-athlete obese men.
Method: In this clinical trial study, sixteen obese healthy non-athletic men randomly divided into intervention and control groups. Subjects in interventional group were practiced endurance running periodic for four weeks, three sessions a week with 65-80% of maximum heart rate. Blood samples collected 48 hours perior the first and 48 hours following the final training. Serum level of Paraoxonase-1 and lipid profile including cholesterol, triglycerides, low-density lipoprotein and high-density lipoprotein were measured by ELISA method.
Results: At the end of the training, the serum level of of paraoxonase -1 increased 15.57% (P
<0.05) in interventional group and non-significantly reduced in control group (19.25%). The serum level of serum Paraoxonase-1 in interventional group significantly increased compared to controls (P<0.05). The serum level of low-density lipoprotein in interventional group significantly reduced in comparision with controls (P<0.05).
Conclusion: 4 weeks of endurance training increased serum level of paraoxonase -1 and decreased lowdensity lipoprotein in non-athlete obese men.

 
Keyword(s): OBESITY, ENDURANCE TRAINING, PARAOXONASE-1 ENZYME, LOW-DENSITY LIPOPROTEIN, HIGH-DENSITY LIPOPROTEIN, MALE
 
References: 
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