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Paper Information

Journal:   JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY   SUMMER 2014 , Volume 9 , Number 2; Page(s) 19 To 27.
 
Paper: 

THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL

 
 
Author(s):  HAJIHASHEMI P., AZADBAKHT L., HASHEMIPOR M., KELISHADI R., ESMAILLZADEH A.*
 
* FOOD SECURITY RESEARCH CENTER, DEPT. OF COMMUNITY NUTRITION, FACULTY OF NUTRITION AND FOOD SCIENCE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

Background and objective: Although whole-grain foods have been reported to affect the metabolic profile, limited data are available in this regard on children. The present study aimed to determine the effects of whole-grain consumption on fasting blood glucose and lipid profile of overweight or obese children.
Materials and methods: This randomized cross-over clinical trial included 44 overweight or obese (BMI>85th percentile for age and sex) girls aged 8-15 years. After a 2-week run-in period, the subjects were randomly assigned to either an intervention or a control group. The subjects in the intervention group were given a list of whole-grain foods (dark bread (sangak and barbari), brown rice, whole-meal biscuits, wheat germ, wheat bran and cornflakes) and asked to choose and consume 50% of their daily grain servings, for 6 weeks, from among whole-grain foods. Those in the control group were given similarly a list of whole-grain foods and asked not to consume any of those foods during the intervention phase of the study. A 4-week washout period was applied following which the subjects were crossed over to the alternate arm for an additional 6 weeks. Fasting blood samples were taken before and after each phase of study for biochemical measurements and metabolic profile determination.
Results: Mean (
±SD) age, body mass index, systolic and diastolic blood pressures of the subjects were 11.2±1.49 years and 23.5±2.5 kg/m2, 111.4±9.7 and 66.4±9.1 mmHg, respectively. After 6 weeks we found significant effects of consuming whole-grain foods on plasma glucose (changes from baseline in the intervention group -1.9 vs.3.8 mg/dL in the control group, P=0.01), serum triglycerides (changes from baseline in the intervention group -16 vs.7 mg/dL in the control group, P=0.01), and serum HDL-cholesterol levels (changes from baseline in the intervention group 6.3 vs. -5.6 mg/dL in the control group, P=0.05). Whole grain intake had no significant effect on serum total and LDL-cholesterol concentrations or blood pressure.
Conclusion: This study provides evidence supporting the beneficial effects of consuming whole-grain foods on the serum levels of fasting blood glucose and lipid profile (TG and HDL) in obese or overweight children.

 
Keyword(s): WHOLE GRAINS, METABOLIC PROFILE, OBESITY, OVERWEIGHT, GIRLS
 
 
References: 
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Click to Cite.
APA: Copy

HAJIHASHEMI, P., & AZADBAKHT, L., & HASHEMIPOR, M., & KELISHADI, R., & ESMAILLZADEH, A. (2014). THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, 9(2), 19-27. https://www.sid.ir/en/journal/ViewPaper.aspx?id=404880



Vancouver: Copy

HAJIHASHEMI P., AZADBAKHT L., HASHEMIPOR M., KELISHADI R., ESMAILLZADEH A.. THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY. 2014 [cited 2021May12];9(2):19-27. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=404880



IEEE: Copy

HAJIHASHEMI, P., AZADBAKHT, L., HASHEMIPOR, M., KELISHADI, R., ESMAILLZADEH, A., 2014. THE EFFECTS OF WHOLE GRAIN INTAKE ON THE METABOLIC PROFILE IN OBESE GIRLS: A CROSSOVER RANDOMIZED CLINICAL TRIAL. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, [online] 9(2), pp.19-27. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=404880.



 
 
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