Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)   NOVEMBER 2013 , Volume 15 , Number 11; Page(s) 15 To 18.
 
Paper: 

EFFECT OF URTICA DIOICA DECOCTION ON SERUM GLUCOSE AND LIPID PROFILE IN STEREPTOZOTOCIN INDUCED DIABETIC MALE RATS

 
 
Author(s):  SAHRAKI MOHAMMAD REZA*, MIRSHEKARI HAMIDEH, SAHRAKI AHMAD REZA, SHAFIGHI ELNAZ
 
* DEPARTMENT OF PHYSIOLOGY, ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES, ZAHEDAN, IRAN
 
Abstract: 

Background: Since Urtica dioica is a traditional treatment plant and is used for antihypertensive, antilipidemic and antidiabetic agents, this survey was carried out to evaluate the effect of Urtica dioica decoction on serum glucose and lipid profile in diabetic male rats induced by stereptozotocin (STZ).
Materials and Methods: This experiment was performed on 30 Wistar-Albino male rats, weighing 200-250 g, which were divided in sham control (A), diabetic control (B) and diabetic test groups (C) randomly (N=10). Type I diabetes was induced by single intraperitoneal injection of STZ (65 mg/kg). Test group received 0.40-0.60 ml of Urtica dioica decoction for a month by gavages, control group (B) received the same volume of distill water. Group (A) did not receive any agent during the experiment period. Finally, animals were anesthetized, sacrificed and blood samples were collected from the cervical vein. Then, serum glucose and lipid profiles were measured by ordinary methods. Data were analyzed by SPSS-11, using ANOVA and post hoc Tukey tests. Results were expressed as mean±SD, and statistical difference was considered significant by p<0.05.
Results: Results in the present study showed that fasting blood glucose (FBS), total cholesterol (TCho), triglyceride (TG), LDL, food and water intake were significantly decreased in group C compared with those of group B, but body weight gain was significantly increased compared with that of control group (B).
Conclusion: These results indicated that Urtica dioica decoction caused decreased FBS and improved serum lipids in diabetic male rats. Some more studies have shown the same mechanism.

 
Keyword(s): URTICA DIOICA, LIPID PROFILES, RAT, GLUCOSE, DIABETES
 
 
References: 
  • ندارد
  •  
 
Click to Cite.
APA: Copy

SAHRAKI, M., & MIRSHEKARI, H., & SAHRAKI, A., & SHAFIGHI, E. (2013). EFFECT OF URTICA DIOICA DECOCTION ON SERUM GLUCOSE AND LIPID PROFILE IN STEREPTOZOTOCIN INDUCED DIABETIC MALE RATS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 15(11), 15-18. https://www.sid.ir/en/journal/ViewPaper.aspx?id=404067



Vancouver: Copy

SAHRAKI MOHAMMAD REZA, MIRSHEKARI HAMIDEH, SAHRAKI AHMAD REZA, SHAFIGHI ELNAZ. EFFECT OF URTICA DIOICA DECOCTION ON SERUM GLUCOSE AND LIPID PROFILE IN STEREPTOZOTOCIN INDUCED DIABETIC MALE RATS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH). 2013 [cited 2021May13];15(11):15-18. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=404067



IEEE: Copy

SAHRAKI, M., MIRSHEKARI, H., SAHRAKI, A., SHAFIGHI, E., 2013. EFFECT OF URTICA DIOICA DECOCTION ON SERUM GLUCOSE AND LIPID PROFILE IN STEREPTOZOTOCIN INDUCED DIABETIC MALE RATS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), [online] 15(11), pp.15-18. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=404067.



 
  pdf-File
Yearly Visit 39
 
Latest on Blog
Enter SID Blog