AN EFFICIENT AND FACILE REGIOSELECTIVE SYNTHESIS OF NEW SUBSTITUTED (E)-1-(3-ARYL-7,8-DIHYDROCINNOLINE-5(6H)-YLIDENE)HYDRAZINES AND (1E, 2E)-1,2-BIS(3-ARYL-7, 8-DIHYDROCINNOLINE-5 (6H)-YLIDENE)HYDRAZINES

A study concerning the new substituted cinnoline synthesis is described. The use of a one-pot three-component method allows a simple regioselective and efficient synthesis of cinnoline derivatives via reaction of arylglyoxals with 1,3-cyclohexanedione and dimedone in the presence of hydrazine hydrate.