Paper Information

Journal:   RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)   2003 , Volume 8 , Number 3 (33); Page(s) 183 To 186.
 
Paper: 

ANXIETY IN PATIENTS HOSPITALIZED IN CCU AND COMPARING DIAZEPAM AND OXAZEPAM EFFECTS

 
 
Author(s):  ZAHIR ALDIN A.R.*, SEMNANI Y.
 
* Department of Psychology, Shaheed Beheshti University of Medical Sciences
 
Abstract: 

Background: Anxiety disorders are one of the most prevalent psychiatric disorders and if not managed properly, would result in many disabilities. Anxiety disorder is more common among patients afflicted by heart disease than in general population and has a negative effect on its course. This study was conducted in Labbafi-Nezhad and Loghman hospitals to determine characteristic of anxiety disorders in patients who admitted at CCU wards and comparing the effects of diazempam and oxazepam.
Materials and methods: First of all, age, sex, history of CCU admission, type of cardiac disease and cardiac drugs were collected sequentially form the files of patients who were admitted at CCU wards, then, anxiety score for each patient was calculated using Hamilton scale, considering patients of score higher than 17 as having anxiety disorder were divided into three groups: two case groups & one control, randomly. Diazepam 6 mg PO daily was given to the first case group, Oxazepam 15 mg PO daily to the 2nd case group and placebo to the control group, then effect of treatment was compared in these three groups.
Results: The study population included 130 males and 68 females with the mean age of 57±12.2 years. The overall prevalence of anxiety was (10.9% in patients with a diagnosis of Myocardial Infarction (MI) and 8.2% in patients with diagnosis of Unstable Angina (UA). There was no significant difference in severity of anxiety disorder between these two groups of patients. Sex and history of CCU admissin had no effect on frequency and severity of anxiety. It was understood that taking benzodiazepines in comparison with placebo decrease the anxiety severity significantly. Myocardial Infraction patients had a better response to diazepam, however UA patients responded much better to oxazepam.
Conclusion: Considering the high prevalence of anxiety disorder in CCU patients, on time diagnosis and treatment would contribute to a patients rehabilitation.

 
Keyword(s): ANXIETY, CCU, MYOCARDIAL INFRACTION UNSTABLE ANGINA
 
References: 
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