Paper Information

Journal:   IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY   Fall 2003 , Volume 9 , Number 2 (34); Page(s) 71 To 76.
 
Paper: 

COMPARISON OF PHENOBARBITAL WITH AMITRIPTYLINE IN PREVENTION OF CHILDREN MIGRAINE

 
 
Author(s):  MIRZAEI MAHMOUD GHOLAM REZA*, DERIS F., PALAHANG H.
 
* Shahr-e-Kord University of Medical Sciences and Health Services, Kashani Hospital, Neurology Ward, Shahr-e-Kord,Iran
 
Abstract: 

Objectives: This research compared the efficacy of Phenobarbital and Amitriptyline in prevention of children migraine headache.
Method: 28 children in two groups of 14 afflicted with migraine headache were matched by age gender and type of migraine. Treatment with the two medications ran for two months. To collect data in addition to clinical interviews by a specialist in neurology a daily form was used to register the frequency and intensity of the attacks. Analysis of data was implemented by t-test.
Findings: Improvement was noted in 28.6% and 42.9% of children who took respectively Phenobarbital and Amitriptyline. The difference between the two groups was not statistically significant. Furthermore the children taking Amitriptyline exhibited more side effects than the other group.
Results: This evaluation revealed that both spoken medicines were effective in prevention of migraine attacks; however considering Phenobarbitals lesser side effects its prescription seems superior in prevention of children migraine.

 
Keyword(s): MIGRAINE, CHILDREN, PHENOBARBITAL, AMITRIPTYLINE
 
References: 
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