Paper Information

Journal:   JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES   Summer 2003 , Volume 12 , Number 46; Page(s) 76 To 83.
 
Paper: 

REASONS OF CHRONIC RENAL FAILURE IN HEMODIALYSIS PATIENTS IN GUILAN PROVINCE

 
 
Author(s):  MONFARED A., ORANGPOUR R., MOUSAVIAN ROUSHAN ZAMIR S.A., AGHAJANI NARGESI D.
 
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Abstract: 

Introduction: Chronic Renal Failure (CRF) is characterized by impaired renal function, which is progressive & irreversible. Most of these patients will need hemodialysis (HD) in future. Treatment of CRF with HD has many economical & psychiatric problems for patients & society.
Objective: The present study was carried out to investigate the reasons of chronic renal failure in hemodialysis patients in Guilan Province.
Materials and Methods: In this cross-sectional study, 414 patients under HD were evaluated in 10 centers in Guilan. Required data were obtained from doctors note, sonography, ECG, renal biopsy & history taking include: age, sex, how long form 1st dialysis & causes of CRF.
Results: In these study 414 cases including 213 (51.4%) male & 201 (48.6%) female were studied. Mean age of patients was 48.9±15.9 in initiation of HD. Results showed that the most common causes of ESRD in this region were hypertension (26.1%), glomerulonephritis (10.9%), diabetes mellitus (10.1%) renal stone (8.7%) and polycystic kidney (6.8%). Other cases such as congenital disease, lupus, Alport syndrome, trauma, bleeding during labor hemorrhagia and drugs were 10.1% and 23.4% were unknown.
Conclusion: The most common causes of End Stage Renal Disease (ESRD) in this region was hypertension (26.1%) and also in this study, glomerulonephritis and diabetes mellitus were second and third causes of ESRD. Also nephrolithiasis, as a cause of CRF was more common in this region. This can be related to probable high-risk prevalence of nephrolithiasis in this region. Causes of CRF between two sexes or age >40 and <40 were different significantly (P<0.05).

 
Keyword(s): HEMODIALYSIS, HYPERTENSION, ACUTE KIDNEY FAILURE
 
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