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Paper Information

Journal:   JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   DECEMBER 2011 , Volume 21 , Number 85; Page(s) 28 To 36.
 
Paper: 

APPLYING SURVIVAL ANALYSIS TO ESTIMATE SURVIVAL TIME IN GASTRIC CANCER PATIENTS

 
 
Author(s):  YAZDANI JAMSHID, SADEGHI SAMANEH, JANBABAEI QASEM, HAGHIGHI FIROOZEH
 
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Abstract: 

Background and purpose: Due to the difficulty of diagnosis, esophageal and gastric cancers have a special position in Mazandaran Province. In this province, gastric cancer is considered to be one the most important causes of mortality; therefore, this study was conducted to investigate the survival of patients with gastric cancer in Mazandaran.
Materials and methods: In this historical Cohort study all gastric cancer patients referring to an academic center clinic from 2007 to 2010 were enrolled. A parametric model was fitted to the data. Parametric survival models, Kaplan-Meier and life table were applied for estimating the survival probability and investigating the effect of different variables.
Results: The mean age of the participants was 64 years and 68.3% of the patients were men. Among the patients, 48.4% were in the most advanced stage i.e.: stage 4. The survival probability of more than 2 years was calculated 27.7% in the patients, using Kaplan Mayer method. Cox hazard proportional model revealed that variables like the stage of the disease, metastasis and surgery status, and age influenced the survival probability of patients.
Conclusion: Low survival time of the participants of the study may be due to the late diagnosis and lack of medical facilities.

 
Keyword(s): GASTRIC CANCER, SURVIVAL, COX MODEL, KAPLAN-MEIER, LIFE TABLE
 
References: 
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