Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   BINA   WINTER 2013 , Volume 18 , Number 2 (71); Page(s) 208 To 221.
 
Paper: 

INTRODUCTION TO CORNEAL STEM CELLS AND OTHER CELLULAR SOURCES FOR TREATMENT OF CORNEAL DISORDERS

 
 
Author(s):  ABEDI MARJAN, AHMADI AZAM, RAHGOZAR SOHEILA*
 
* ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

Stem cell therapy has been applied for the treatment of degenerative diseases encompassing corneal disorders.This consideration is regarding the unique characteristics of stem cells including self-renewal and pluripotency. Some corneal diseases result from deficiencies in the limbal region. In these conditions, limbal stem cell therapy is considered in which limbal stem cells are cultured in vitro and transplanted. However, allograft stem cell transplants may be rejected and the use of immonosuppressors may have adverse effects.
Patient’s epithelial cells are suggested as a source for corneal stem cells. Animal studies have shown successful differentiation of hair follicle, dental pulp, bone marrow, oral mucus and mesenchymal stem cells to corneal epithelial cells. In this revie warticle, the corneal stem cells are first introduced. Various stem cell cultures are then discussed and the possibility of using other stem cell sources for the treatment of corneal disorders is evaluated.

 
Keyword(s): CORNEAL DISORDERS, STEM CELLS, LIMBAL REGION, CELL CULTURE
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 58
 
Latest on Blog
Enter SID Blog