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Paper Information

Journal:   BINA   FALL 2012 , Volume 18 , Number 1 (70); Page(s) 52 To 56.
 
Paper: 

CORNEAL CROSS-LINKING FOR PSEUDOPHAKIC BULLOUS KERATOPATHY

 
 
Author(s):  MIRZAIE M.*, RAHBANI NOBAR M.B., LOTFI SEDIGH A., MIRZAIE S.
 
* TABRIZ UNIVERSITY OF MEDICAL SCIENCES, TABRIZ, IRAN
 
Abstract: 

Purpose: To evaluate the efficacy of riboflavin administration and ultraviolet A (UVA) cross-linking on advanced symptomatic bullous keratopathy (BK).
Methods: 10 patients with symptomatic pseudophakic bullous keratopathy (PBK) were included. Slit-lamp examination, visual acuity, foreign body sensation (FBS) and corneal thickness as measured by Pentacam, were performed before corneal cross-linking. After using sodium chloride solution for one week, the central 8 mm zone of the corneal epithelium was removed, and cross-linking, with riboflavin instillation every 3 minutes for 30 minutes, and UVA irradiation for 40 minutes was performed. VA, FBS and corneal thickness were evaluated up to 6 months.
Results: Three male and 7 female patients with mean age of 66±13 years were included. Mean follow-up duration was 6.2 months. VA increased in 9 eyes postoperatively, FBS subsided in 70% of patients. Mean corneal thickness was reduced by 74mm 6 months after the procedure (P=0.059).
Conclusion: Collagen cross linking for BK improves FBS & VA and decreases corneal thickness; this extends the time interval for corneal transplantation and improves visualization for DSAEK procedures.

 
Keyword(s): BULLOUS KERATOPATHY, CROSS-LINKING, CORNEAL EDEMA, CORNEAL THICKENING
 
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