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Paper Information

Journal:   BINA   FALL 2012 , Volume 18 , Number 1 (70); Page(s) 30 To 38.
 
Paper: 

OUTCOMES OF SINGLE-SITE PHACOTRABECULECTOMY WITH MITOMYCIN C

 
 
Author(s):  SEDIGHI A., JAVADI M.A.*, FEIZI S., YASERI M.
 
* OPHTHALMIC RESEARCH CENTER, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Purpose: To evaluate visual outcomes and intraocular pressure (IOP) after Single-site phacotrabeculectomy with mitomycin C in patients with senile cataract and primary open angle glaucoma (POAG), pseudoexfoliative glaucoma (PXG), or chronic angle closure glaucoma (CACG).
Methods: In this retrospective study, patients older than 50 years who had significant cataracts (BCVA20.60) and uncontrolled POAG, PXG, or PACG (IOP>21 mmHg with at least two anti-glaucoma medications) were enrolled.
Exclusion criteria included the presence of corneal pathologies, uveitis, diabetic retinopathy, neovascular or phacomorphic glaucoma, posterior segment pathologies, or a history of ocular trauma or intraocular surgery.
Preoperative examination included uncorrected and best-corrected visual acuity (UCVA and BCVA, respectively), slit lamp biomicroscopy, IOP measurements, gonioscopy, and dilated funduscopy. The participants underwent single site phacotrabeculectomy with mitomycin C. Postoperative follow-up examinations were scheduled on days 1, 3, 7, and 14, and months 1, 3 and every 3 months thereafter. In each follow-up examination, the patients were re-evaluated for BCVA, IOP, the number of anti-glaucoma medications if needed, appearance of the bleb, and postoperative complications.
Results: Forty (24 right) eyes of 32 (12 female) patients with POAG (15 eyes), PXG (18 eyes), or CACG (7 eyes) were enrolled. Mean patient age was 73±9 (range, 46 to 88) years and the study groups were comparable in this regard (P=0.88). Mean postoperative follow-up period was 13.1±9.5 months, raging from 1 to 40 months. Of the participants, 6 had diabetes mellitus and 6 had systemic hypertension. Mean preoperative BCVA was 0.64±0.32 logMAR (20/80) which improved to 0.38±0.19 logMAR (20/50) postoperatively (P<0.001). Preoperatively, mean IOP was 18.6±6.0 (range, 7 to 33) mmHg which was decreased to 12.3±3.0 (range, 6 to 17) mmHg postoperatively (P< 0.001).The PXG group demonstrated the highest reduction (P=0.001) and the POAG group experienced the lowest reduction (P=0.021) in IOP. At the last follow-up examination, the number of anti-glaucoma medications was reduced to 0.9±1.1, on average (P<0.001). The reduction in the number of medication was highest in the POAG (2.1±1.1, P=0.001) and lowest in the CAGC group (1.3±0.5, P=0.08). At final follow-up IOP was controlled with no medications in 21 eyes (52.5%), with timolol in 8 eyes (20%), and with 2 or more medications in 11 eyes (27.5%). With respect to intra- and postoperative complications and the appearance of the bleb, the study groups were comparable.
Conclusion: One-site phacotrabeculectomy with mitomycin C is a safe and effective approach to decrease IOP and improve BCVA in patients with coexisting cataract and glaucoma.

 
Keyword(s): ONE-SITE PHACOTRABECULECTOMY, SENILE CATARACT, PRIMARY OPEN ANGLE GLAUCOMA, PSEUDOEXFOLIATIVE GLAUCOMA, CHRONIC ANGLE CLOSURE GLAUCOMA
 
 
References: 
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Click to Cite.
APA: Copy

SEDIGHI, A., & JAVADI, M., & FEIZI, S., & YASERI, M. (2012). OUTCOMES OF SINGLE-SITE PHACOTRABECULECTOMY WITH MITOMYCIN C. BINA, 18(1 (70)), 30-38. https://www.sid.ir/en/journal/ViewPaper.aspx?id=277013



Vancouver: Copy

SEDIGHI A., JAVADI M.A., FEIZI S., YASERI M.. OUTCOMES OF SINGLE-SITE PHACOTRABECULECTOMY WITH MITOMYCIN C. BINA. 2012 [cited 2021May06];18(1 (70)):30-38. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=277013



IEEE: Copy

SEDIGHI, A., JAVADI, M., FEIZI, S., YASERI, M., 2012. OUTCOMES OF SINGLE-SITE PHACOTRABECULECTOMY WITH MITOMYCIN C. BINA, [online] 18(1 (70)), pp.30-38. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=277013.



 
 
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