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Paper Information

Journal:   BINA   SUMMER 2012 , Volume 17 , Number 4 (69); Page(s) 333 To 338.
 
Paper: 

CORNEAL GRAFT BIOMECHANICS AFTER PENETRATING KERATOPLASTY IN KERATOCONUS

 
 
Author(s):  FEIZI S.*, YAZDANI S., MALEKIFAR P., JAVADI M.A., HASANPOUR H.
 
* OPHTHALMIC RESEARCH CENTER, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Purpose: To evaluate corneal hysteresis and corneal resistance factor in penetrating keratoplasty grafts in a group of keratoconic eyes using the ocular response analyzer (ORA) and to evaluate the relationship between donor size, donor-recipient disparity and central graft thickness (CGT), and ORA parameters.
Methods: This cross-sectional study was conducted on 34 eyes of 34 keratoconus patients who had undergone PKP. Corneal hysteresis (CH), corneal resistance factor (CRF), and cornea-compensated intraocular pressure were measured at least 6 months after complete suture removal. Two groups of donorrecipient disparity (0.25 vs. 0.50 mm) were compared using the independent t test. Multivariate regression analysis was used to investigate the correlation of donor trephine size and CGT with ORA parameters. Factors influencing intraocular pressure measured with the Goldmann applanation tonometer (IOP GAT) after PKP were determined using multiple regression analysis.
Results: Mean patient age and follow-up period were 29.6
±6.2 years and 82.4±59.6 months, respectively. Mean CGT, CH, and CRF were 567.5±38.8 mm, 10.2±2.1 mm Hg, and 10.1±2.2 mm Hg, respectively. CH and CRF had a significant positive correlation with donor trephine size and CGT. Significantly greater values of CH and CRF were observed in the 0.5-mm disparity group compared with the 0.25-mm disparity group. Among the studied parameters, only CH, CRF, and cornea-compensated intraocular pressure had a significant positive correlation with IOP GAT.
Conclusion: Graft biomechanics seem to be closer to normal values with larger grafts and greater donorrecipient disparity. These metrics had a significant correlation with IOP GAT after PKP.

 
Keyword(s): KERATOCONUS, PENETRATING KERATOPLASTY, GRAFT BIOMECHANICS
 
 
References: 
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Citations: 
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APA: Copy

FEIZI, S., & YAZDANI, S., & MALEKIFAR, P., & JAVADI, M., & HASANPOUR, H. (2012). CORNEAL GRAFT BIOMECHANICS AFTER PENETRATING KERATOPLASTY IN KERATOCONUS. BINA, 17(4 (69)), 333-338. https://www.sid.ir/en/journal/ViewPaper.aspx?id=276952



Vancouver: Copy

FEIZI S., YAZDANI S., MALEKIFAR P., JAVADI M.A., HASANPOUR H.. CORNEAL GRAFT BIOMECHANICS AFTER PENETRATING KERATOPLASTY IN KERATOCONUS. BINA. 2012 [cited 2021July23];17(4 (69)):333-338. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276952



IEEE: Copy

FEIZI, S., YAZDANI, S., MALEKIFAR, P., JAVADI, M., HASANPOUR, H., 2012. CORNEAL GRAFT BIOMECHANICS AFTER PENETRATING KERATOPLASTY IN KERATOCONUS. BINA, [online] 17(4 (69)), pp.333-338. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276952.



 
 
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