Paper Information

Journal:   INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY   OCTOBER-DECEMBER 2012 , Volume 6 , Number 3; Page(s) 179 To 184.
 
Paper:  CLINICAL VARIABLES AFFECTING THE PREGNANCY RATE OF INTRACERVICAL INSEMINATION USING CRYOPRESERVED DONOR SPERMATOZOA: A RETROSPECTIVE STUDY IN CHINA
 
Author(s):  CHEN XIAO JUN, WU LI PING, LAN HAI LIAN, ZHANG LI, YI MIN ZHU*
 
* DEPARTMENT OF REPRODUCTIVE ENDOCRINOLOGY, WOMEN’S HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY, HANGZHOU, ZHEJIANG, CHINA
 
Abstract: 
Background: The aim of this study was to investigate whether several clinical variables can affect the pregnancy rate of intracervical insemination (ICI) using cryopreserved donor spermatozoa.
Materials and Methods: In this retrospective study, age, years of infertility, cervicitis, urinary luteinizing hormone (LH) surge, insemination number, uterus position, endometrial thickness and morphology, maximal follicle diameter, and the number of dominant follicles on the day of human chorionic gonadotropin (HCG) administration were retrospectively analyzed in 501 women who underwent their first ICI cycle using cryopreserved donor spermatozoa.
Results: Increased age, length of infertility (>5 years), retroverted uterine position, and endometrial thickness (<7 mm or>14 mm) were associated with lower rates of pregnancy.
Conclusion: In older women with infertile periods longer than five years, especially those with a retroverted uterus, intrauterine insemination (IUI) combined with ovarian stimulation should be recommended.
In vitro fertilization with donor spermatozoa (IVFD) should be offered earlier to achieve a much higher success rate.
 
Keyword(s): SEMEN DONOR, ARTIFICIAL INSEMINATION, PREGNANCY RATE
 
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