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Paper Information

Journal:   INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY   OCTOBER-DECEMBER 2012 , Volume 6 , Number 3; Page(s) 175 To 178.
 
Paper: 

EFFECT OF ADDING HUMAN CHORIONIC GONADOTROPIN TO THE ENDOMETRIAL PREPARATION PROTOCOL IN FROZEN EMBRYO TRANSFER CYCLES

 
 
Author(s):  EFTEKHAR MARYAM, RAHMANI ELHAM*, EFTEKHAR TAHEREH
 
* DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, BUSHEHR UNIVERSITY OF MEDICAL SCIENCES, BUSHEHR, IRAN
 
Abstract: 
Background: Human chorionic gonadotropin (HCG), one of the initial embryonic signals, is probably a major regulator of the embryo-endometrial relationship. This study aims to assess the advantage of HCG supplementation during the secretory phase of hormonally prepared cycles for the transfer of cryopreserved-thawed embryos.
Materials and Methods: This study was a randomized clinical trial. Infertile women who were candidates for frozen-thawed embryo transfers entered the study and were divided into two groups, HCG and control. The endometrial preparation method was similar in both groups: all women received estradiol valerate (6 mg) po per day from the second day of the menstrual cycle and progesterone in oil (100 mg) intramuscular (I.M.) when the endometrial thickness reached 8 mm. Estradiol and progesterone were continued until the tenth week of gestation. In the HCG group, patients received an HCG 5000 IU injection on the first day of progesterone administration and the day of embryo transfer.
Results: In this study, 130 couples participated: 65 in the HCG group and 65 in the control group.
There was no statistically significant difference between groups regarding basic characteristics.
Implantation rate, chemical pregnancy, clinical pregnancy, ongoing pregnancy, and abortion rates were similar in both groups.
Conclusion: Although HCG has some advantages in assisted reproductive technology (ART) cycles, our study did not show any benefit of HCG supplementation during the secretory phase of frozen cycles (Registration Number: IRCT201107266420N4).
 
Keyword(s): ART, IMPLANTATION, FROZEN EMBRYO, HCG
 
 
References: 
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Citations: 
 
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APA: Copy

EFTEKHAR, M., & RAHMANI, E., & EFTEKHAR, T. (2012). EFFECT OF ADDING HUMAN CHORIONIC GONADOTROPIN TO THE ENDOMETRIAL PREPARATION PROTOCOL IN FROZEN EMBRYO TRANSFER CYCLES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 6(3), 175-178. https://www.sid.ir/en/journal/ViewPaper.aspx?id=276383



Vancouver: Copy

EFTEKHAR MARYAM, RAHMANI ELHAM, EFTEKHAR TAHEREH. EFFECT OF ADDING HUMAN CHORIONIC GONADOTROPIN TO THE ENDOMETRIAL PREPARATION PROTOCOL IN FROZEN EMBRYO TRANSFER CYCLES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY. 2012 [cited 2021July28];6(3):175-178. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276383



IEEE: Copy

EFTEKHAR, M., RAHMANI, E., EFTEKHAR, T., 2012. EFFECT OF ADDING HUMAN CHORIONIC GONADOTROPIN TO THE ENDOMETRIAL PREPARATION PROTOCOL IN FROZEN EMBRYO TRANSFER CYCLES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, [online] 6(3), pp.175-178. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276383.



 
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