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Paper Information

Journal:   JOURNAL OF OPHTHALMIC AND VISION RESEARCH   JULY 2011 , Volume 6 , Number 3; Page(s) 155 To 159.
 
Paper: 

SHORT-TERM OUTCOMES OF COLLAGEN CROSSLINKING FOR EARLY KERATOCONUS

 
 
Author(s):  DERAKHSHAN AKBAR*, HERAVIAN SHANDIZ JAVAD, AHADI MASUMEH, DANESHVAR RAMIN, ESMAILY HABIBOLLAH
 
* DEPARTMENT OF OPHTHALMOLOGY, KHATAM-AL-ANBIA HOSPITAL, MASHHAD UNIVERSITY OF MEDICAL SCIENCES, GHARANI AVE., MASHHAD 91767, IRAN
 
Abstract: 

Purpose: To assess the efficacy of collagen crosslinking with riboflavin and ultraviolet A (UVA) radiation for treatment of early keratoconus.
Methods: Thirty-one eyes of 22 patients with early keratoconus were included in this study. All patients underwent slit lamp examination and assessment of uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), intraocular pressure, corneal topography and pachymetry. Collagen crosslinking was performed without epithelial removal. Riboflavin was applied to the cornea every 3 minutes 30 minutes before UVA irradiation and every 5 minutes thereafter. Patients were re-assessed 1, 3, and 6 months after treatment.
Results: Postoperatively, UCVA increased by 2 Snellen lines and BSCVA was improved by 1.7 Snellen lines (P<0.001). Spherical equivalent refractive error was reduced by 0.55 D, and maximum and mean K values were decreased by 0.65 D and 0.51 D respectively (P<0.05 for all comparisons). Evidence of regression was present in 71% of treated eyes.
Conclusion: Collagen crosslinking demonstrated significant improvement in vision with reduction in corneal power and spherical equivalent refractive error in eyes with early keratoconus.

 
Keyword(s): CORNEA, KERATOCONUS, RIBOFLAVIN, UVA RADIATION, COLLAGEN CROSSLINKING
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

DERAKHSHAN, A., & HERAVIAN SHANDIZ, J., & AHADI, M., & DANESHVAR, R., & ESMAILY, H. (2011). SHORT-TERM OUTCOMES OF COLLAGEN CROSSLINKING FOR EARLY KERATOCONUS. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 6(3), 155-159. https://www.sid.ir/en/journal/ViewPaper.aspx?id=276260



Vancouver: Copy

DERAKHSHAN AKBAR, HERAVIAN SHANDIZ JAVAD, AHADI MASUMEH, DANESHVAR RAMIN, ESMAILY HABIBOLLAH. SHORT-TERM OUTCOMES OF COLLAGEN CROSSLINKING FOR EARLY KERATOCONUS. JOURNAL OF OPHTHALMIC AND VISION RESEARCH. 2011 [cited 2021July25];6(3):155-159. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276260



IEEE: Copy

DERAKHSHAN, A., HERAVIAN SHANDIZ, J., AHADI, M., DANESHVAR, R., ESMAILY, H., 2011. SHORT-TERM OUTCOMES OF COLLAGEN CROSSLINKING FOR EARLY KERATOCONUS. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, [online] 6(3), pp.155-159. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276260.



 
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