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Paper Information

Journal:   IRANIAN JOURNAL OF EPIDEMIOLOGY   FALL 2007-WINTER 2008 , Volume 3 , Number 3-4; Page(s) 21 To 27.
 
Paper: 

CONTAMINATION OF DRINKING WATER WITH ARSENIC AND ITS VARIOUS HEALTH EFFECTS IN THE VILLAGE OF GHOPUZ

 
 
Author(s):  HOSSEINPOUR FEIZI M.A., MOSAFERI M.*, DASTGIRI S., ZOLALI SH., POULADI N., AZARFAM P.
 
* DEPARTMENT OF ENVIRONMENTAL HEALTH ENGINEERING, SCHOOL OF HEALTH AND NUTRITION, NATIONAL PUBLIC HEALTH MANAGEMENT CENTER, TABRIZ UNIVERSITY OF MEDICAL SCIENCES, TABRIZ
 
Abstract: 

Background & Objectives: Arsenicosis is a serious environmental disease caused by chronic exposure to arsenic- usually from drinking water. Signs and symptoms of chronic arsenic poisoning include hyperkeratosis, hyper- or hypopigmentation, and ulcers. Also, the incidence of cancer is increased in the exposed population. There is some evidence of high arsenic levels in drinking water in the village of Ghopuz, located in Hashtrud District, East Azerbaijan province. We evaluated the genetic and health effects of chronic arsenic exposure in the residents of Ghopuz.
Methods: In this cross-sectional study we determined the prevalence of hyperkeratosis, hyperpigmentation and hypertension in Ghopuz village. The study involved 101 individuals in Ghopuz and 107 in the adjacent village of Mayan, who were all visited by a trained physician. A total of 46 blood samples were collected for kariotyping. The level of heavy metals in water was determined by the Inductively Coupled Plasma (ICP) method.
Results: We detected high arsenic levels in the drinking water at Ghopuz (mean concentration in water=1.03 mg/L). There were chromosomal defects in the exposed group. Mean systolic blood pressure at Ghopuz (137mmHg, 95% CI: 132-142) was significantly higher than in Mayan (107, 95% CI: 99.9-114). Also, mean diastolic blood pressure at Ghopuz (82, 95% CI: 79-85) was significantly higher than in Mayan (71, 95% CI: 66-75). Hyperkeratosis was 34 times more frequent in the exposed population (OR=34, P<0.001). Also, hyperpigmentation was significantly more frequent in the exposed population (OR=2.4, P<0.007).
Conclusions: Water arsenic and nitrate levels at Ghopuz were higher than the maximum permissible levels. The prevalence of skin lesions and hypertension is increased at Ghopuz village due to arsenic exposure. There is also some evidence of chromosomal defects in the exposed group. Affected people need appropriate medical care, and safe drinking water should be provided to reduce arsenic exposure.

 
Keyword(s): ARSENIC, DRINKING WATER, CHROMOSOMAL ABNORMALITIES, SKIN LESIONS, HYPERTENSION, EAST AZERBAIJAN
 
 
References: 
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APA: Copy

HOSSEINPOUR FEIZI, M., & MOSAFERI, M., & DASTGIRI, S., & ZOLALI, S., & POULADI, N., & AZARFAM, P. (2008). CONTAMINATION OF DRINKING WATER WITH ARSENIC AND ITS VARIOUS HEALTH EFFECTS IN THE VILLAGE OF GHOPUZ. IRANIAN JOURNAL OF EPIDEMIOLOGY, 3(3-4), 21-27. https://www.sid.ir/en/journal/ViewPaper.aspx?id=276065



Vancouver: Copy

HOSSEINPOUR FEIZI M.A., MOSAFERI M., DASTGIRI S., ZOLALI SH., POULADI N., AZARFAM P.. CONTAMINATION OF DRINKING WATER WITH ARSENIC AND ITS VARIOUS HEALTH EFFECTS IN THE VILLAGE OF GHOPUZ. IRANIAN JOURNAL OF EPIDEMIOLOGY. 2008 [cited 2021July26];3(3-4):21-27. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276065



IEEE: Copy

HOSSEINPOUR FEIZI, M., MOSAFERI, M., DASTGIRI, S., ZOLALI, S., POULADI, N., AZARFAM, P., 2008. CONTAMINATION OF DRINKING WATER WITH ARSENIC AND ITS VARIOUS HEALTH EFFECTS IN THE VILLAGE OF GHOPUZ. IRANIAN JOURNAL OF EPIDEMIOLOGY, [online] 3(3-4), pp.21-27. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276065.



 
 
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