Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)   WINTER 2012 , Volume 2 , Number 6; Page(s) 52 To 61.
 
Paper: 

BLOOD LOSS AND QUALITY OF CONTROLLED HYPOTENSION INDUCED BY MAGNESIUM SULFATE VERSUS REMIFENTANIL IN PSF SURGERY

 
 
Author(s):  HOMAEE MOHAMMADMOHSEN, GHODRATI MOHAMMADREZA*, FARAZMEHR KOUROSH, SOLEIMANI MASOUD, POURNAJAFIAN ALIREZA, ABDAVI AZAR SHARBIANI MAJID
 
* FIROUZGAR HOSPITAL, TEHRAN, IRAN
 
Abstract: 

Aim and Background: Blood loss is one of the most critical problems in major surgery. Spinal surgery usually associated with considerable blood loss and allogeneic transfusions. Controlled hypotension is one of efficient methods for decreasing operative blood loss. The objective of this study was evaluation of the efficacy of magnesium sulfate in comparison with remifentanil for induction of relative hypotension in posterior fusion of spine surgery.
Methods and Materials: In this double blind randomized clinical trial, 40 patients with ASA I & II physical status candidate for lumbar posterior spinal fusion surgery were enrolled and assigned in two groups (remifentanil and magnesium sulfate) randomly. After the induction of anesthesia and giving the prone position, relative controlled hypotension was induced for one group with 0.15
mg/kg remifentanil infusions and in second group with 50 mg/kg loading dose and then 15 mg/kg/hr magnesium sulfate infusion. All other aspects of anesthesia and surgery were similar in two groups. The target MAP range used in this study was 60-70 mmhg. In the course of surgery the hemodynamic variables, volume of blood loss, urine output, fluid intake and surgeon’s satisfaction were recorded. Data was analyzed with SPSS version 13 software and P- value less than 0.05 was considered meaningful.
Findings: Twenty patients in Mg group and 19 patients in remifentanil group were studied. There was no statistical difference between two groups according to the hemodynamic variables, volume of blood loss, urine output, fluid intake and surgeon's satisfaction (p>0.05). The target mean arterial pressure was achieved in 75% of Mg and 58% of remifentanil groups. Although, the frequency of TNG consumption was higher (42.1%) in remifentanil group than magnesium sulfate (25%), but this difference wasn't statistically significant (p=0.320).
Conclusions: Our finding showed that in patients undergoing lumbar posterior spinal fusion surgery, remifentanil and magnesium sulfate has the same hypotensive effect and the volume of blood loss without any significant side effects.

 
Keyword(s): CONTROLLED HYPOTENSION, MAGNESIUM SULFATE, REMIFENTANIL, LUMBAR POSTERIOR SPINE FUSION (PSF), BLOOD LOSS, CLINICAL TRIAL
 
 
References: 
  • Not Registered.
  •  
  •  
 
Citations: 
  • Not Registered.
 
+ Click to Cite.
APA: Copy

HOMAEE, M., & GHODRATI, M., & FARAZMEHR, K., & SOLEIMANI, M., & POURNAJAFIAN, A., & ABDAVI AZAR SHARBIANI, M. (2012). BLOOD LOSS AND QUALITY OF CONTROLLED HYPOTENSION INDUCED BY MAGNESIUM SULFATE VERSUS REMIFENTANIL IN PSF SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 2(6), 52-61. https://www.sid.ir/en/journal/ViewPaper.aspx?id=276046



Vancouver: Copy

HOMAEE MOHAMMADMOHSEN, GHODRATI MOHAMMADREZA, FARAZMEHR KOUROSH, SOLEIMANI MASOUD, POURNAJAFIAN ALIREZA, ABDAVI AZAR SHARBIANI MAJID. BLOOD LOSS AND QUALITY OF CONTROLLED HYPOTENSION INDUCED BY MAGNESIUM SULFATE VERSUS REMIFENTANIL IN PSF SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN). 2012 [cited 2021July25];2(6):52-61. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276046



IEEE: Copy

HOMAEE, M., GHODRATI, M., FARAZMEHR, K., SOLEIMANI, M., POURNAJAFIAN, A., ABDAVI AZAR SHARBIANI, M., 2012. BLOOD LOSS AND QUALITY OF CONTROLLED HYPOTENSION INDUCED BY MAGNESIUM SULFATE VERSUS REMIFENTANIL IN PSF SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), [online] 2(6), pp.52-61. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=276046.



 
 
Persian Abstract Yearly Visit 35
 
 
Latest on Blog
Enter SID Blog