Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY   FALL 2012 , Volume 22 , Number 3 (69); Page(s) 211 To 215.
 
Paper: 

FACTORS AFFECTING PREGNANCY AND ABORTION RATES FOLLOWING INTRA CYTOPLASMIC SPERM INJECTION IN THE OBSTRUCTIVE AND NONOBSTRUCTIVE AZOOSPERMIC MEN

 
 
Author(s):  HASHEMIAN NAEINI ELHAMOSSADAT, AKBARI ASBAGH FIROOZEH, ZARE NIYESTANAK MOHAMMAD, MEHRSAI ABDOLRASOL, FOROOZANDEH ELHAM, SHOKOUHI MOSTAFA, BERJIS KATAYOON*
 
* BOO-ALI HOSPITAL, TEHRAN, IRAN
 
Abstract: 

Background: Intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of azoospermic men. The aim of this study was to evaluate the factors interfering in the success of ICSI, including sperm collection method, testicular histology, age and hormonal assay of the couple, the number of retrieved oocytes, and the number of transferred embryos.
Materials and methods: In this retrospective cohort study, 246 azoospemic men (52 with obstructive azoosprmia (OA) and 194 with non-obstructive azoospermia (NOA)) who were underwent sperm retrieval with PESA or TESE and ICSI protocol were studied. By long protocol of ovarian stimulation, oocytes were retrieved 36h after hCG administration. After 48h, cleaved embryos were replaced in the uterine cavity.
Results: Clinical pregnancy rates (21.1% in OA versus 10.8% in NOA) was significantly correlated with sperm origin (P<0.05). Female partner’s age and serum FSH significantly influenced pregnancy rates in both groups (p<0.001) and also pregnancy rates was significantly influenced by number of retrieved oocytes and transferred embryos in NOA groups (P<0.05).
Conclusion: ICSI can make a chance for fertility in azoospermic men. Higher success rates in OA patients can be related to better quality of sperm. The value of male hormonal assay and testicular biopsy was not remarkable.

 
Keyword(s): OBSTRUCTIVE AZOOSPRMIA, NON OBSTRUCTIVE AZOOSPERMIA, ICSI, CLINICAL PREGNANCY RATES
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 54
 
Latest on Blog
Enter SID Blog