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Paper Information

Journal:   JOURNAL OF CELL & TISSUE   SPRING 2012 , Volume 3 , Number 1; Page(s) 65 To 72.
 
Paper: 

RESEARCH ARTICLE: THE ANTIOXIDANT EFFECT OF VITAMIN C ON DECREASING THE INDUCED CHROMOSOMAL DAMAGES BY LOW-FREQUENCY ELECTROMAGNETIC FIELD ON BONE MARROW ERYTHROCYTES OF MALE BALB/C MOUSE

 
 
Author(s):  BAHARARA J.*, HADDAD F., ASHRAF A.R., SADEGH MOGHADDAM ABBASPOUR R.
 
* DEPARTMENT OF BIOLOGY, FACULTY OF SCIENCE, MASHHAD BRANCH, ISLAMIC AZAD UNIVERSITY, MASHHAD, IRAN
 
Abstract: 

Aim: In the present study, the antioxidant effect of vitamin C on decreasing the induced chromosomal damages by low-frequency electromagnetic field on bone marrow erythrocytes of male Balb/C mouse has been investigated.
Material and Methods: In this experimental study, 48 adult male mouse (Balb/C) were randomly divided into four equal groups: control, test 1, test 2 and test 3. Control group were kept in normal conditions and the mice in test1 and test3 groups were intraperitoneally injected with 50 mg / kg of vitamin C for 8 consecutive days. Then the mice of test 3 and test 2 groups after the fifth day were exposed to electromagnetic waves with frequency of 50 Hz and intensity of 50 Gauss for 4 days and 4 hours per day. The mice in all different groups were sacrificed and micronucleus test were performed on the bone marrow polychromatic erythrocytes. The data were analyzed using spss software and ANOVA test at level p<0.05.
Results: The frequency of micronucleus in bone marrow polychromatic erythrocytes of test3 group (3.107±0.276) in comparison with test 2 group (9.29±0.881) showed a significant reduction (p<0.001).
Conclusion: Vitamin C caused significant decrease in induced chromosomal damages by low-frequency electromagnetic waves in bone marrow polychromatic erythrocytes of adult male Balb/C mouse.

 
Keyword(s): ANTIOXIDANT, BALB/ C, ELECTROMAGNETIC WAVES, ERYTHROCYTES, VITAMIN C
 
 
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APA: Copy

BAHARARA, J., & HADDAD, F., & ASHRAF, A., & SADEGH MOGHADDAM ABBASPOUR, R. (2012). RESEARCH ARTICLE: THE ANTIOXIDANT EFFECT OF VITAMIN C ON DECREASING THE INDUCED CHROMOSOMAL DAMAGES BY LOW-FREQUENCY ELECTROMAGNETIC FIELD ON BONE MARROW ERYTHROCYTES OF MALE BALB/C MOUSE. JOURNAL OF CELL & TISSUE, 3(1), 65-72. https://www.sid.ir/en/journal/ViewPaper.aspx?id=275870



Vancouver: Copy

BAHARARA J., HADDAD F., ASHRAF A.R., SADEGH MOGHADDAM ABBASPOUR R.. RESEARCH ARTICLE: THE ANTIOXIDANT EFFECT OF VITAMIN C ON DECREASING THE INDUCED CHROMOSOMAL DAMAGES BY LOW-FREQUENCY ELECTROMAGNETIC FIELD ON BONE MARROW ERYTHROCYTES OF MALE BALB/C MOUSE. JOURNAL OF CELL & TISSUE. 2012 [cited 2021August05];3(1):65-72. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=275870



IEEE: Copy

BAHARARA, J., HADDAD, F., ASHRAF, A., SADEGH MOGHADDAM ABBASPOUR, R., 2012. RESEARCH ARTICLE: THE ANTIOXIDANT EFFECT OF VITAMIN C ON DECREASING THE INDUCED CHROMOSOMAL DAMAGES BY LOW-FREQUENCY ELECTROMAGNETIC FIELD ON BONE MARROW ERYTHROCYTES OF MALE BALB/C MOUSE. JOURNAL OF CELL & TISSUE, [online] 3(1), pp.65-72. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=275870.



 
 
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