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Paper Information

Journal:   JOURNAL OF MEDICAL COUNCIL OF I.R.I.   FALL 2007 , Volume 25 , Number 3; Page(s) 292 To 298.
 
Paper: 

A SURVEY OF BRAIN ABSCESS SURGERY OUTCOMES IN SHOHADA HOSPITAL DURING 1994-2003

 
 
Author(s):  ZALI A., BORZOOYEH F., TAHERZADEH K.
 
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Abstract: 

Background: Despite technological advancements in diagnostic and therapeutic procedures, brain abscess is a potentially fatal disease and it carries significant morbidity and mortality. The goal of this study was to define the outcome of brain abscess operations in Shohada Hospital during ten years.
Methods: This existing data study was carried out using hospital records of patients with brain abscess operated in Shohada Hospital between the years 1994 and 2003. The clinical information and outcomes of surgeries were extracted and then analyzed.
Findings: Data of 78 records showed that the most common etiology was congenital heart disease (37.2%). The most frequent clinical manifestations were focal neurological deficit (75.6%), headache (64.1%) and vomiting (60.3%). 57.7% of cases had full consciousness and the remaining had altered level of consciousness. Overall, 137 surgery procedures were performed, with 35.5% of cases cured, 22% resulted in morbidity and 31% in mortality. 11.5% of patients either left the hospital without any further treatment or were referred to another medical center. 76% of cultures from abscesses were negative. The highest mortality was related with excision operation (23.1%) and congenital heart disease (33.3%). The majority of recurrences occurred after aspiration (41.3%) and greater morbidity followed excision operations (23.1%).
Conclusion: Given the relatively high prevalence of brain abscess - as an important and fatal complication - among patients with heart diseases and patients with other predisposing factors, it is recommended that CT scan be performed for the sake of earlier diagnosis and timely treatment, and ultimate reduction of mortality and morbidity in these individuals. Also, most of cultures were negative in our study which is due to inadequate availability to anaerobic and fungal culture media or inappropriate sampling techniques.

 
Keyword(s): BRAIN ABSCESS, SURGERY OUTCOME, MORTALITY, MORBIDITY, CONGENITAL HEART DISEASE
 
References: 
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