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Paper Information

Journal:   IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)   MAY 2012 , Volume 14 , Number 1 (SN 61); Page(s) 63 To 67.
 
Paper: 

RELATED FACTORS OF ACUTE LEUKEMIA IN CHILDREN AND THE ROLE OF BREAST FEEDING

 
 
Author(s):  NIKPOUR S.*, RAHIMIAN SH., SHOKRABI S., HAGHANI H.
 
* NURSING CARE RESEARCH CENTER, TEHRAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, TEHRAN, I.R. IRAN
 
Abstract: 

Introduction: In this study we aimed to determine factors related to the etiology of cancer in children.
Materials and Methods: We investigated this issue in a case control study of 300 patients, aged 2±14 years, with acute leukemia, and 300 controls, individually matched to cases for age and sex, and place of residence. Children were enrolled after selection by a continuous sampling method. Information regarding breast-feeding was obtained through face to face interviews with mothers.
Results: Breastfeeding for durations less than one month increased the risk for childhood acute leukemia. Also, results showed that children 18-13 months and 24-19 months were breast fed, respectively, 2.45 and 3.54 times less than had been breastfed children under 1 year were diagnosed with acute leukemia. (P<0.05). Higher number of children (OR=1.42, CI 1.03-1.96) and low family income (OR=0.6, CI 0.38-1.01) increased the risk for childhood acute leukemia (p<0.05).
Conclusion: Results of this study indicate that childhood acute leukemia may be associated with breast-feeding, economic status, and number of children. Further cohort studies on factors causing acute Leukemia in children are recommended.

 
Keyword(s): BREAST-FEEDING, RELATED FACTORS, ACUTE LEUKEMIA, CASE-CONTROL STUDY
 
References: 
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