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Paper Information

Journal:   IRANIAN HEART JOURNAL (IHJ)   FALL 2012 , Volume 13 , Number 3; Page(s) 27 To 32.
 
Paper: 

A COMPARATIVE ANALYSIS OF THE LEVEL OF HIGH SENSITIVE C-REACTIVE PROTEIN IN PEOPLE WITH AND WITHOUT HYPERTENSION

 
 
Author(s):  NAGHSHTABRIZI BEHSHAD, MOZAYANIMONFARED AZADEH, EMAMI FARZAD, DADRAS FARAHNAZ, GHARAKHANI MOHSEN*
 
* DEPARTMENT OF CARDIOLOGY, SCHOOL OF MEDICINE, HAMEDAN UNIVERSITY OF MEDICAL SCIENCES, HAMEDAN, ISLAMIC REPUBLIC OF IRAN
 
Abstract: 
Background: High sensitive C-reactive protein (hs-CRP) is an available measured serum marker for detecting blood vessel inflammation and endothelial dysfunction. It has been demonstrated that these two mechanisms have a pivotal role in the pathogenesis and progression of hypertension. We conjecture and confirm in this study that the level of hs-CRP is higher in hypertensive patients.
Methods: We enrolled 77 hypertensive patients with the following distribution in the case group (male: 27.7%, female: 72.3%, mean age: 58.1 years, mean systolic blood pressure: 15.4 mm Hg, mean diastolic blood pressure: 90.4 mm Hg) and 77 matched normotensives, in the control group. Patients with heart failure, renal failure (cr>2mg/dl,) diabetes mellitus, infective disorder, severe systemic disorder and malignancies were excluded. Blood pressure was measured using the same digital Richter sphygmomanometer (ceo124 Ri-fit.) The hs-CRP was measured using CRP HS ELISA (enzyme immunoassay for quantitative determination of CRP in human serum). The normal range was 0.068–8.2 mg/l. Finally, the data were analyzed using SSPS-10 software.
Results: The mean levels of hs-CRP in the case and control groups were 4.29 and 2.43 respectively (p value<0.001).
Conclusion: Our study showed that the level of hs-CRP was elevated in the hypertensive patients, which reflected the role of the inflammatory process in the pathogenesis of hypertension.
 
Keyword(s): HS-CRP, LOW-GRADE INFLAMMATION, HYPERTENSION
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

NAGHSHTABRIZI, B., & MOZAYANIMONFARED, A., & EMAMI, F., & DADRAS, F., & GHARAKHANI, M. (2012). A COMPARATIVE ANALYSIS OF THE LEVEL OF HIGH SENSITIVE C-REACTIVE PROTEIN IN PEOPLE WITH AND WITHOUT HYPERTENSION. IRANIAN HEART JOURNAL (IHJ), 13(3), 27-32. https://www.sid.ir/en/journal/ViewPaper.aspx?id=275465



Vancouver: Copy

NAGHSHTABRIZI BEHSHAD, MOZAYANIMONFARED AZADEH, EMAMI FARZAD, DADRAS FARAHNAZ, GHARAKHANI MOHSEN. A COMPARATIVE ANALYSIS OF THE LEVEL OF HIGH SENSITIVE C-REACTIVE PROTEIN IN PEOPLE WITH AND WITHOUT HYPERTENSION. IRANIAN HEART JOURNAL (IHJ). 2012 [cited 2021August04];13(3):27-32. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=275465



IEEE: Copy

NAGHSHTABRIZI, B., MOZAYANIMONFARED, A., EMAMI, F., DADRAS, F., GHARAKHANI, M., 2012. A COMPARATIVE ANALYSIS OF THE LEVEL OF HIGH SENSITIVE C-REACTIVE PROTEIN IN PEOPLE WITH AND WITHOUT HYPERTENSION. IRANIAN HEART JOURNAL (IHJ), [online] 13(3), pp.27-32. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=275465.



 
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