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Paper Information

Journal:   JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES   SPRING 2012 , Volume 4 , Number 1 (11); Page(s) 7 To 12.
 
Paper: 

EFFECTS OF AMPHOTERICIN B VERSUS GLUCANTIME AS FIRST LINE OF TREATMENT IN VISCERAL LEISHMANIASIS

 
DOI: 

10.29252/jnkums.4.1.7

 
Author(s):  BANIHASHEM A., HEYDARIAN F.*, HIRADFAR S., NOURI M., KHAKSHOUR A., SHOJA M.
 
* PEDIATRICS WARDS GHAEM HOSPITAL, MASHHAD, IRAN
 
Abstract: 

Background & Objectives: Currently glucantime is used as first choice drug in treating kala- azar. Because of some rising unresponsiveness to this drug, in this study we attempt to compare glucantime with amphotericin B in treatment of kala-azar as first line of therapy.
Material & Methods: In these prospective study 19 patients aged 6.5 months to 10 years old with kalaazar were assessed. 12 out of 19 cases received amphotericn B and remainder treated with glucantime.
Results: Fever and throm bocytopenia were improved more rapidly in amphotericin B taking group. (P 0.05 and P 0.017 respectively).
Two cases were died who belonged to glucantime treated group (p 0.02) all patients who received amphotericin B were successfully cured.
Conclusion: Am photericin B can cure kalazar fully with improving fever and thrombocytopenia quicker than glucantime.

 
Keyword(s): KALA-AZAR, AMPHOTERICIN B, GLUCANTIME
 
 
References: 
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Click to Cite.
APA: Copy

BANIHASHEM, A., & HEYDARIAN, F., & HIRADFAR, S., & NOURI, M., & KHAKSHOUR, A., & SHOJA, M. (2012). EFFECTS OF AMPHOTERICIN B VERSUS GLUCANTIME AS FIRST LINE OF TREATMENT IN VISCERAL LEISHMANIASIS. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, 4(1 (11)), 7-12. https://www.sid.ir/en/journal/ViewPaper.aspx?id=274411



Vancouver: Copy

BANIHASHEM A., HEYDARIAN F., HIRADFAR S., NOURI M., KHAKSHOUR A., SHOJA M.. EFFECTS OF AMPHOTERICIN B VERSUS GLUCANTIME AS FIRST LINE OF TREATMENT IN VISCERAL LEISHMANIASIS. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES. 2012 [cited 2021May06];4(1 (11)):7-12. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=274411



IEEE: Copy

BANIHASHEM, A., HEYDARIAN, F., HIRADFAR, S., NOURI, M., KHAKSHOUR, A., SHOJA, M., 2012. EFFECTS OF AMPHOTERICIN B VERSUS GLUCANTIME AS FIRST LINE OF TREATMENT IN VISCERAL LEISHMANIASIS. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, [online] 4(1 (11)), pp.7-12. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=274411.



 
 
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