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Paper Information

Journal:   JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES   FALL 2012 , Volume 14 , Number 3 (43); Page(s) 109 To 114.
 
Paper: 

VERBAL FLUENCY AND WORKING MEMORY DEFICIT IN FIRST-DEGREE RELATIVES OF AUTISTIC CHILDREN

 
 
Author(s):  NEJATI V.*, IZADI NAJAFABADI S.
 
* DEPARTMENT OF COGNITIVE NEUROSCIENCE (BRAIN AND COGNITION), SHAHID BEHESHTI UNIVERSITY, TEHRAN, IRAN
 
Abstract: 

Background and Objective: Autism spectrum disorder is a genetic-based cognitive and neurobehavioral disorder characterized by impairment in social interaction, verbal and non-verbal communication and repetitive motor behavior. This study was done to evaluate the verbal fluency and working memory deficit in first-degree relatives of autistic children.
Materials and Methods: In this case-control study, 49 first-degree relatives of autistic children from 33 families (32 mothers, 10 fathers, 6 sisters, and 1 brother) supported by Isfahan autism association were selected and compared with 51 first-degree relatives of typical children (23 mothers, 16 fathers, 7 sisters, and 5 brothers) of 27 families during 2010. The assessing tasks were phonemic and semantic verbal fluency tests to assess verbal fluency and forward and backward digiti span tests to assess low load and high load working memory. Data were analyzed using SPSS-19 and independent t-test and paired t-test.
Results: Autistic relatives showed significant poor performance in phonemic (11.46
±3.3 V.S. 14.08±3.8), semantic verbal fluency (16.83±3.3 V.S. 19.23±3.9), forward digiti span (5.22±0.6 V.S. 5.55±0.9) and backward digiti span (3.65±0.98 V.S. 4.14±0.8) (P<0.05) compared to healthy children of first-degree relatives.
Conclusion: This study showed that parents and siblings of autistic children have a lower performance in phonemic and semantic, low and high load verbal fluency, which might be transmitted genetically.

 
Keyword(s): VERBAL FLUENCY, WORKING MEMORY, FIRST-DEGREE RELATIVES, AUTISM
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

NEJATI, V., & IZADI NAJAFABADI, S. (2012). VERBAL FLUENCY AND WORKING MEMORY DEFICIT IN FIRST-DEGREE RELATIVES OF AUTISTIC CHILDREN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 14(3 (43)), 109-114. https://www.sid.ir/en/journal/ViewPaper.aspx?id=274021



Vancouver: Copy

NEJATI V., IZADI NAJAFABADI S.. VERBAL FLUENCY AND WORKING MEMORY DEFICIT IN FIRST-DEGREE RELATIVES OF AUTISTIC CHILDREN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES. 2012 [cited 2021July27];14(3 (43)):109-114. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=274021



IEEE: Copy

NEJATI, V., IZADI NAJAFABADI, S., 2012. VERBAL FLUENCY AND WORKING MEMORY DEFICIT IN FIRST-DEGREE RELATIVES OF AUTISTIC CHILDREN. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, [online] 14(3 (43)), pp.109-114. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=274021.



 
 
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