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Paper Information

Journal:   IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN)   FEBRUARY-MARCH 2012 , Volume 24 , Number 6 (ISSUE NUMBER 116); Page(s) 494 To 503.
 
Paper: 

FUNCTIONALITY EFFECT OF ACRYLIC PRESSURE SENSITIVE ADHESIVE FORMULATIONS ON RELEASE PERFORMANCE AND ADHESION PROPERTIES OF STIMULANTS IN AN ADHESIVE PATCH

 
 
Author(s):  TAGHIZADEH S. MOJTABA*, JOORABLOO ALI REZA
 
* IRAN POLYMER AND PETROCHEMICAL INSTITUTE, TEHRAN, IRAN
 
Abstract: 

Drug-in-adhesive transdermal drug delivery systems (TDDSs) containing stimulants, termed as energetic substances, such as caffeine and pantothenic acid, were studied. Caffeine is a white crystalline substance and a stimulant to central nervous system. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Pantothenic acid, also recognized as vitamin B5, is a water-soluble vitamin. For many animals, pantothenic acid is an essential nutrient. Animals require pantothenic acid to synthesize and metabolize proteins, carbohydrates and fats. For this purpose caffeine and pantothenic acid were used as drug components with 6.32% and 1.12% loadings, in different functional and non-functional acrylic pressure sensitive adhesives (PSAs) of 52.89%, respectively. Ethylene glycol as a chemical enhancer was used in all TDDSs with 39.67%. The effect of PSAs type on in vitro release and adhesion properties (peel strength and tack values) from drug delivery devices were evaluated. It was found that TDDS containing -COOH functional PSA showed the lowest steady state flux. The adhesion properties of the samples were improved by addition of functional acrylic PSA in formulations.

 
Keyword(s): FUNCTIONALITY, TRANSDERMAL DRUG DELIVERY SYSTEM, RELEASE, ADHESION PROPERTIES, PRESSURE SENSITIVE ADHESIVE
 
 
References: 
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Click to Cite.
APA: Copy

TAGHIZADEH, S., & JOORABLOO, A. (2012). FUNCTIONALITY EFFECT OF ACRYLIC PRESSURE SENSITIVE ADHESIVE FORMULATIONS ON RELEASE PERFORMANCE AND ADHESION PROPERTIES OF STIMULANTS IN AN ADHESIVE PATCH. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN), 24(6 (ISSUE NUMBER 116)), 494-503. https://www.sid.ir/en/journal/ViewPaper.aspx?id=273926



Vancouver: Copy

TAGHIZADEH S. MOJTABA, JOORABLOO ALI REZA. FUNCTIONALITY EFFECT OF ACRYLIC PRESSURE SENSITIVE ADHESIVE FORMULATIONS ON RELEASE PERFORMANCE AND ADHESION PROPERTIES OF STIMULANTS IN AN ADHESIVE PATCH. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN). 2012 [cited 2021May10];24(6 (ISSUE NUMBER 116)):494-503. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273926



IEEE: Copy

TAGHIZADEH, S., JOORABLOO, A., 2012. FUNCTIONALITY EFFECT OF ACRYLIC PRESSURE SENSITIVE ADHESIVE FORMULATIONS ON RELEASE PERFORMANCE AND ADHESION PROPERTIES OF STIMULANTS IN AN ADHESIVE PATCH. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN), [online] 24(6 (ISSUE NUMBER 116)), pp.494-503. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273926.



 
 
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