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Paper Information

Journal:   RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)   JANUARY 2011 , Volume 18 , Number 91; Page(s) 1 To 6.
 
Paper: 

THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT

 
 
Author(s):  FARAMARZI AZITA, SEIFI BEHJAT, SOHANI MAHSA, SADEGHIPOUR RODSARI HAMID REZA*
 
* DEPARTMENT OF PHYSIOLOGY, SCHOOL OF MEDICINE, TEHRAN UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Background: Vasectomy is a widespread contraceptive method in men. In recent years, the number of men who perform vasectomy reversal is increasing. Vasectomy has complications, probably leading to vasectomy reversal failure. It is assumed that oxidative stress is the main cause of these complications. The aim of this study was to investigate the indices of oxidative stress serum after vasectomy.
Methods: In this experimental study, 42 male rats were divided in 6 groups of seven each: bilateral vasectomy (15, 45 and 90 days) and sham (15, 45 and 90 days) groups. Serum PAB (Prooxidant- Antioxidant Balance) and MDA (Malondialdehyde) as a product of lipid peroxidation were measured 15, 45 and 90 days after intervention. Comparisons between groups were made by Repeated Measure test.
Results: Our result showed that serum MDA increase after 15 days was not significant (2.95±0.12) in comparison to related sham group, but after 45 (3.6±0.12) and 90 (3.9±0.31) days the increase, compared to related sham groups 45 (2.28±0.28) and 90 (2.29±0.25)days, and also 15 days vasectomy group (2.95±0.12) were significant (p<0.001), and there was no significant increase in serum PAB at any times (p>0.05).
Conclusion: Bilateral vasectomy increased serum levels of MDA. It is supposed that increase in MDA causes adverse effects and unsuccessful reversal vasectomy. By prescribing antioxidants, these effects can be decreased.

 
Keyword(s): VASECTOMY, PROOXIDANT-ANTIOXIDANT BALANCE, MALONDIALDEHYDE, RAT
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

FARAMARZI, A., & SEIFI, B., & SOHANI, M., & SADEGHIPOUR RODSARI, H. (2011). THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 18(91), 1-6. https://www.sid.ir/en/journal/ViewPaper.aspx?id=273612



Vancouver: Copy

FARAMARZI AZITA, SEIFI BEHJAT, SOHANI MAHSA, SADEGHIPOUR RODSARI HAMID REZA. THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES). 2011 [cited 2021July30];18(91):1-6. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273612



IEEE: Copy

FARAMARZI, A., SEIFI, B., SOHANI, M., SADEGHIPOUR RODSARI, H., 2011. THE EFFECT OF BILATERAL VASECTOMY ON THE SERUM LEVELS OF PROOXIDANT-ANTIOXIDANT BALANCE (PAB) AND LIPID PEROXIDATION IN RAT. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), [online] 18(91), pp.1-6. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273612.



 
 
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