The aim of this article was to describe the clinical management of a case with seizure, possibly due to iron deficiency anaemia (IDA) in a kitten. A 38-day-old female European shorthair cat was presented with acute onset of impaired consciousness, seizures and lateralised upper motor neuron tetraparesis. Haematology results showed severe microcytic hypochromic anaemia with marked anisocytosis and thrombocytosis, while a low plasma iron concentration (<0.9 µmol/L) was the most remarkable biochemical alteration encountered. Iron deficiency anaemia was suspected and oral iron therapy was started together with supportive treatment. The cat responded to therapy and clinical signs started to improve on the second day and returned to normal eight days after referral to the clinic.