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Paper Information

Journal:   IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY   SUMMER 2012 , Volume 2 , Number 3; Page(s) 94 To 98.
 
Paper: 

EFFECT OF 1.25 (OH)2-VITAMINE D ON BONE MINERAL DENSITY IN CHILDHOOD ACUTE LEUKEMIA

 
 
Author(s):  NAMJOU Z., GHILIAN R.*, HASHEMI A., VOJDANIFARD F., BAKHSHI F., DEHGHANI KH.
 
* DEPARTMENT OF INTERNAL MEDICINE, SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, YAZD, IRAN
 
Abstract: 

Background: Bone mineral density (BMD) may be occurred following treatment of acute lymphoblastic Leukemia (ALL). 25-hydroxyvitamin D insufficiency has been described in these patients. In this Randomized Control Trial (RCT) we assessed the effectiveness of oral vitamin D administration after one year of treatment to protect bone density.
Materials and Methods: Twenty-four survivors of ALL (17 males and 7 females), who had completed their treatment with oral vitamin D supplement, at least 1 yr previously, and Twenty-five (20 males and 5 females) control group were examined with dual energy x-ray absorptiometry of the total body and L2–L4 vertebrae and neck of femur.
Result: Average of BMD (g/cm2) was significantly increased in oral vitamin D supplemented children (p=0.038) but average of Z-score decrease (p=0.006). Osteoporosis in this group was 4.2% and in lortnoc group, 40.9%.
Conclusion: Oral vitamin D supplementation to ALL children during 1 year did not show impact on Z-score and BMD (g/cm2). In the other hand osteoporosis decreased in this group.

 
Keyword(s): LEUKEMIA, VITAMIN D, BONE DENSITY
 
 
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APA: Copy

NAMJOU, Z., & GHILIAN, R., & HASHEMI, A., & VOJDANIFARD, F., & BAKHSHI, F., & DEHGHANI, K. (2012). EFFECT OF 1.25 (OH)2-VITAMINE D ON BONE MINERAL DENSITY IN CHILDHOOD ACUTE LEUKEMIA. IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY, 2(3), 94-98. https://www.sid.ir/en/journal/ViewPaper.aspx?id=273300



Vancouver: Copy

NAMJOU Z., GHILIAN R., HASHEMI A., VOJDANIFARD F., BAKHSHI F., DEHGHANI KH.. EFFECT OF 1.25 (OH)2-VITAMINE D ON BONE MINERAL DENSITY IN CHILDHOOD ACUTE LEUKEMIA. IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY. 2012 [cited 2021July26];2(3):94-98. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273300



IEEE: Copy

NAMJOU, Z., GHILIAN, R., HASHEMI, A., VOJDANIFARD, F., BAKHSHI, F., DEHGHANI, K., 2012. EFFECT OF 1.25 (OH)2-VITAMINE D ON BONE MINERAL DENSITY IN CHILDHOOD ACUTE LEUKEMIA. IRANIAN JOURNAL OF PEDIATRIC HEMATOLOGY AND ONCOLOGY, [online] 2(3), pp.94-98. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=273300.



 
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